ArticleNature medicine2024
Reply to: Challenges to identifying risk versus protective factors in Alzheimer's disease.
Abstract readLetter
In one paragraph
Article in Nature medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Trial
- Molecular programs in human locus coeruleus link APOE and neuromelanin to Alzheimer's vulnerability.Acta neuropathologica · 2026Article
- Novel predictors of Alzheimer's disease in Down syndrome identified using machine learning.Journal of Alzheimer's disease : JAD · 2025Article
- Generational effects in Down syndrome: Enriched environment enhances functionality without reducing Alzheimer's disease risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Arhgef7 as a key target for enriched environment rescuing spatial cognitive deficits and anxiety-like behaviors in a mouse model of Alzheimer's disease following early social isolation.Alzheimer's research & therapy · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Juan Fortea *Sant Pau Memory Unit, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau, Barcelona, Spain. jfortea@santpau.cat.ORCID http://orcid.org/0000-0002-1340-638X
Lídia Vaqué-AlcázarSant Pau Memory Unit, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau, Barcelona, Spain.
Jordi PeguerolesSant Pau Memory Unit, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau, Barcelona, Spain.
Daniel AlcoleaSant Pau Memory Unit, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau, Barcelona, Spain.ORCID http://orcid.org/0000-0002-3819-3245
Olivia BelbinSant Pau Memory Unit, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau, Barcelona, Spain.ORCID http://orcid.org/0000-0002-6109-6371
Oriol Dols-IcardoSant Pau Memory Unit, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau, Barcelona, Spain.ORCID http://orcid.org/0000-0003-2656-8748
Laura VidelaSant Pau Memory Unit, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau, Barcelona, Spain.ORCID http://orcid.org/0000-0002-9748-8465
Juan Domingo GispertBarcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.
Marc Suárez-CalvetBarcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.ORCID http://orcid.org/0000-0002-2993-569X
Sterling C JohnsonWisconsin Alzheimer's Disease Research Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.ORCID http://orcid.org/0000-0002-8501-545X
Reisa SperlingBrigham and Women's Hospital Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-1535-6133
Alexandre BejaninSant Pau Memory Unit, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau, Barcelona, Spain.ORCID http://orcid.org/0000-0002-9958-0951
Alberto LleóSant Pau Memory Unit, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau, Barcelona, Spain.ORCID http://orcid.org/0000-0002-2568-5478
Víctor Montal *Sant Pau Memory Unit, Hospital de la Santa Creu i Sant Pau - Biomedical Research Institute Sant Pau, Barcelona, Spain.ORCID http://orcid.org/0000-0002-5714-9282
Funding
University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9MTHE ROLE OF ADVANCED CAA IN ALZHEIMER'S DEMENTIAP50AG005134 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI HYMAN, BRADLEY T. · 1985 to 2018
$42.1MWisconsin Alzheimer's Disease Research CenterP50AG033514 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI SAGER, MARK · 2009 to 2018
$16.2MClinical trials to prevent Alzheimer's Disease in Down SyndromeR61AG066543 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI RAFII, MICHAEL S · 2019 to 2020
$5.6MBiograph Horizon PET/CTS10OD025245 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI CHRISTIAN, BRADLEY T · 2018 to 2018
$1.3MAlzheimer's Association AARF-22-924456Alzheimer's Association AARG-22-923680EC | EU Framework Programme for Research and Innovation H2020 | H2020 The European Institute of Innovation and Technology | EIT Digital (EIT Digital IVZW) Grant 2021EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) H2020-SC1-BHC-2018-2020Fundación Tatiana Pérez de Guzmán el Bueno (Tatiana Pérez Foundation of Guzmán el Bueno) IIBSP-DOW-2020-151Generalitat de Catalunya (Government of Catalonia) SLT002/16/00408Generalitat de Catalunya (Government of Catalonia) SLT006/17/00119"la Caixa" Foundation (Caixa Foundation) LCF/PR/GN17/50300004Ministry of Economy and Competitiveness | Instituto de Salud Carlos III (Institute of Health Carlos III) CD23/00235Ministry of Economy and Competitiveness | Instituto de Salud Carlos III (Institute of Health Carlos III) CP20/00038, PI22/00307Ministry of Economy and Competitiveness | Instituto de Salud Carlos III (Institute of Health Carlos III) INT21/00073, PI20/01473 and PI23/01786Ministry of Economy and Competitiveness | Instituto de Salud Carlos III (Institute of Health Carlos III) PI18/00435Ministry of Economy and Competitiveness | Instituto de Salud Carlos III (Institute of Health Carlos III) PI20/01330Ministry of Economy and Competitiveness | Instituto de Salud Carlos III (Institute of Health Carlos III) PI22/00456NCATS NIH HHS UL1 TR002373NIA NIH HHS P50 AG005134NIA NIH HHS P50 AG033514NIA NIH HHS R61 AG066543U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01 AG027161, R01 AG021155, R01 AG037639, R01 AG054059; P50 AG033514 and P30 AG062715U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01 AG056850; R21 AG056974, R01 AG061566, R01 AG081394 and R61AG066543U.S. Department of Health & Human Services | National Institutes of Health (NIH) S10 OD025245, P30 AG062715, U54 HD090256, UL1 TR002373, P01 AG036694 and P50 AG005134
Abstract
PubMed holds no abstract for this paper.
Identifiers
PMID
39025967What OpenQuestion holds
Textmetadata
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.