Evidence map›Paper›PMID 39025953›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2025

Retrospective study of preterm infants exposed to inhaled nitric oxide in Kaiser Permanente Southern California: morbidity, mortality and follow-up.

Dilip R Bhatt, David Braun, Roman Angelo Dizon, Jiaxiao M Shi, Sunjeeve Weerasinghe, Alex Sabio, Siva Reddy, Henry C Lee, Rangasamy Ramanathan, Satyan Lakshminrusimha

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dilip R BhattFontana Medical Center, Kaiser Permanente Southern California, Fontana, CA, USA.
David BraunDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA. david.x.braun@kp.org.ORCID http://orcid.org/0000-0001-9048-0164
Roman Angelo DizonFontana Medical Center, Kaiser Permanente Southern California, Fontana, CA, USA.
Jiaxiao M ShiDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA.
Sunjeeve WeerasingheFontana Medical Center, Kaiser Permanente Southern California, Fontana, CA, USA.
Alex SabioFontana Medical Center, Kaiser Permanente Southern California, Fontana, CA, USA.
Siva ReddyFontana Medical Center, Kaiser Permanente Southern California, Fontana, CA, USA.
Henry C LeeUniversity of California, San Diego, CA, USA.
Rangasamy RamanathanDivision of Neonatology, Cedars Sinai Guerin Children's, Cedars Sinai Medical Center, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-7358-601X
Satyan LakshminrusimhaUC Davis Children's Hospital, Sacramento, CA, USA.ORCID http://orcid.org/0000-0001-6098-2155

Funding

Optimal Oxygenation in Neonatal Lung InjuryR01HD072929 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Satyanarayana Lakshminrusimha · 2012 to 2026
$5.4M
NICHD NIH HHS R01 HD072929U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) R01 HD 072929
6 · The paper itself

Abstract

objectiveDescribe characteristics of preterm infants exposed to inhaled nitric oxide (iNO) in Kaiser Permanente Southern California. STUDY

designCase review of preterm infants <34-weeks exposed to iNO during 2010-2020 including respiratory and echocardiographic status, NICU course, and 12-month follow-up.

results270 infants, 2.63% of births<34 weeks, (median, range: 26.1, 22

conclusionsPreterm infants receiving iNO have high mortality and 1st year morbidity. As currently used, iNO may be an indicator of respiratory disease severity rather than mediator of improved outcomes.

Indexed as

Bronchodilator AgentsInfant, Premature, DiseasesNitric OxideAdministration, InhalationCaliforniaFemaleFollow-Up StudiesGestational AgeHumansHypertension, PulmonaryInfantInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalMaleRetrospective StudiesBronchodilator AgentsNitric Oxide

Identifiers

PMID39025953
PMCPMC12069078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.