Evidence map›Paper›PMID 39025892›Full record

ArticleScientific reports2024

A multi-center analysis of visual outcomes following open globe injury.

Jason A Greenfield, Davina A Malek, Shruti Anant, Michael Antonietti, Alessandro Jammal, Alicia Casella, Sarah C Miller, Kristine Wang, Bita Momenaei, Karen Lee and 10 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Overnight vs. daytime surgical repair in open globe injuries and their association with long-term visual outcomes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Jason A GreenfieldBascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17Th Street, Miami, FL, 33136, USA.
Davina A MalekBascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17Th Street, Miami, FL, 33136, USA.
Shruti AnantWilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD, USA.
Michael AntoniettiBascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17Th Street, Miami, FL, 33136, USA.
Alessandro JammalBascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17Th Street, Miami, FL, 33136, USA.
Alicia CasellaBascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17Th Street, Miami, FL, 33136, USA.
Sarah C MillerWilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD, USA.
Kristine WangWills Eye Hospital, Jefferson Health, Philadelphia, PA, USA.
Bita MomenaeiWills Eye Hospital, Jefferson Health, Philadelphia, PA, USA.
Karen LeeWills Eye Hospital, Jefferson Health, Philadelphia, PA, USA.
Hana A MansourWills Eye Hospital, Jefferson Health, Philadelphia, PA, USA.
Grant A JustinDuke Department of Ophthalmology, Duke University, Durham, NC, USA.
Kevin G MakhoulMassachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Racquel A BitarMassachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Alice C LorchMassachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Grayson W ArmstrongMassachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Taku WakabayashiWills Eye Hospital, Jefferson Health, Philadelphia, PA, USA.
Yoshihiro YonekawaWills Eye Hospital, Jefferson Health, Philadelphia, PA, USA.
Fasika WoretaWilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD, USA.
Kara CavuotoBascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17Th Street, Miami, FL, 33136, USA. kcavuoto@med.miami.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to examine how demographics, etiology, and clinical examination findings are related to visual outcomes in subjects with open globe injury (OGI) across a large and generalizable sample. A retrospective cohort analysis was performed using data collected from the electronic medical records of four tertiary university centers for subjects with OGI presenting from 2018 to 2021. Demographic information, injury mechanisms, clinical exam findings, visual acuity (VA) at presentation and most recent follow-up were recorded. In subjects with bilateral OGIs, only right eyes were included. A modified ocular trauma score (OTS) using presenting VA, the presence of perforating injury, OGI, and afferent pupillary defect was calculated. The risk of subjects' demographic characteristics, ocular trauma etiology, clinical findings and modified OTS on the presence of monocular blindness at follow-up were assessed using univariable and multivariable regression models. 1426 eyes were identified. The mean age was 48.3 years (SD: ± 22.4 years) and the majority of subjects were men (N = 1069, 75.0%). Univariable analysis demonstrated that subjects of Black race were 66% (OR: 1.66 [1.25-2.20]; P < 0.001) more likely to have monocular blindness relative to White race at follow-up. OTS Class 1 was the strongest predictor of blindness (OR: 38.35 [21.33-68.93]; P < 0.001). Based on multivariable analysis, lower OTS category (OTS Class 1 OR: 23.88 [16.44-45.85]; P < 0.001) moderately predicted visual outcomes (R

Indexed as

Eye Injuries, PenetratingVisual AcuityAdolescentAdultAgedBlindnessFemaleHumansMaleMiddle AgedRetrospective StudiesYoung AdultEtiologyOcular traumaOpen globe injuryVisual outcome

Identifiers

PMID39025892
PMCPMC11258120

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.