Evidence map›Paper›PMID 39025869›Full record

ArticleNPJ science of learning2024

Parental education and children's depression, anxiety, and ADHD traits, a within-family study in MoBa.

Amanda M Hughes, Fartein Ask Torvik, Elsje van Bergen, Laurie J Hannigan, Elizabeth C Corfield, Ole A Andreassen, Eivind Ystrom, Helga Ask, George Davey Smith, Neil M Davies and 1 more

Abstract read
In one paragraph

Article in NPJ science of learning, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. ADHD, social skills and risky internet use among elementary school children.Child and adolescent psychiatry and mental health · 2025
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amanda M HughesMRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol, UK. amanda.hughes@bristol.ac.uk.ORCID http://orcid.org/0000-0001-5896-7650
Fartein Ask TorvikCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.ORCID http://orcid.org/0000-0003-3984-5978
Elsje van BergenDepartment of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0002-5860-5745
Laurie J HanniganNic Waals Institute, Lovisenberg Diaconal Hospital, Oslo, Norway.
Elizabeth C CorfieldNic Waals Institute, Lovisenberg Diaconal Hospital, Oslo, Norway.ORCID http://orcid.org/0000-0002-0119-157X
Ole A AndreassenNORMENT Centre, Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, 0407, Oslo, Norway.ORCID http://orcid.org/0000-0002-4461-3568
Eivind YstromPromenta Research Centre, Department of Psychology, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0003-4390-6171
Helga AskPromenta Research Centre, Department of Psychology, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0003-0149-5319
George Davey SmithMRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-1407-8314
Neil M DaviesDivision of Psychiatry, University College London, London, UK.ORCID http://orcid.org/0000-0002-2460-0508
Alexandra HavdahlMRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol, UK.

Funding

Causes and consequences of mental disorders: The environmental and genetic influences of parents on offspring.R01MH130448 · NIMH · UNIVERSITY OF COLORADO · PI Matthew Charles Keller · 2022 to 2026
$3.7M
EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 101076726EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) FAMILY; grant agreement no. 101057529EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) Marie Skłodowska-Curie grant agreement ESSGN 101073237Medical Research Council MC_UU_00032/1Ministry of Health and Care Services | Helse Sør-Øst RHF (Southern and Eastern Norway Regional Health Authority) 2019097Ministry of Health and Care Services | Helse Sør-Øst RHF (Southern and Eastern Norway Regional Health Authority) 2020022Ministry of Health and Care Services | Helse Sør-Øst RHF (Southern and Eastern Norway Regional Health Authority) 2021045Ministry of Health and Care Services | Helse Sør-Øst RHF (Southern and Eastern Norway Regional Health Authority) 2922083Nederlandse Organisatie voor Wetenschappelijk Onderzoek (Netherlands Organisation for Scientific Research) 024-001-003NIMH NIH HHS R01 MH130448Norges Forskningsråd (Research Council of Norway) 274611Norges Forskningsråd (Research Council of Norway) 288083Norges Forskningsråd (Research Council of Norway) 295989Norges Forskningsråd (Research Council of Norway) 336078Norges Forskningsråd (Research Council of Norway) 336085Norges Forskningsråd (Research Council of Norway) Norges ForskningsrådRCUK | MRC | Medical Research Foundation MC_UU_00032/1
6 · The paper itself

Abstract

Children born to parents with fewer years of education are more likely to have depression, anxiety, and attention-deficit hyperactivity disorder (ADHD), but it is unclear to what extent these associations are causal. We estimated the effect of parents' educational attainment on children's depressive, anxiety, and ADHD traits at age 8 years, in a sample of 40,879 Norwegian children born in 1998-2009 and their parents. We used within-family Mendelian randomization, which employs genetic variants as instrumental variables, and controlled for direct genetic effects by adjusting for children's polygenic indexes. We found little evidence that mothers' or fathers' educational attainment independently affected children's depressive, anxiety, or ADHD traits. However, children's own polygenic scores for educational attainment were independently and negatively associated with these traits. Results suggest that differences in these traits according to parents' education may reflect direct genetic effects more than genetic nurture. Consequences of social disadvantage for children's mental health may however be more visible in samples with more socioeconomic variation, or contexts with larger socioeconomic disparities than present-day Norway. Further research is required in populations with more educational and economic inequality and in other age groups.

Identifiers

PMID39025869
PMCPMC11258307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.