Evidence map›Paper›PMID 39025048›Full record

ReviewJournal of innate immunity2024

The Roles of Innate Immune Cells in Atopic Dermatitis.

Yuke Pan, Youyi Wang, Meinian Xu, Meizhen Zhong, Xiaoming Peng, Kang Zeng, Xiaowen Huang

Abstract readReview
In one paragraph

Review in Journal of innate immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuke PanThe First School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Youyi WangDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, China, sx520159@smu.edu.cn.
Meinian XuDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Meizhen ZhongDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Xiaoming PengDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Kang ZengDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Xiaowen HuangDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtopic dermatitis (AD) is a chronic inflammatory skin condition characterized by recurrent eczematous lesions and severe pruritus. The economic burden and time penalty caused by the relapse of AD reduce patients' life quality. SUMMARY: AD has complex pathogenesis, including genetic disorders, epidermal barrier dysfunction, abnormal immune responses, microbial dysbiosis of the skin, and environmental factors. Recently, the role of innate immune cells in AD has attracted considerable attention. This review highlighted recent findings on innate immune cells in the onset and progression of AD. KEY MESSAGES: Innate immune cells play essential roles in the pathogenesis of AD and enough attention should be given for treating AD from the perspective of innate immunity in clinics.

Indexed as

Dermatitis, AtopicImmunity, InnateAnimalsHumansSkinAdaptive immunityAlarminsAtopic dermatitisDamage-associated molecular patternsInnate immune cellsInnate immunityPathogen-associated molecular patternsPRRsPruritus

Identifiers

PMID39025048
PMCPMC11324229

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.