Evidence map›Paper›PMID 39024782›Full record

ArticleChild abuse & neglect2024

Childhood maltreatment and substance use risk: A moderated mediation model of autonomic reactivity and distress tolerance.

Joshua T McMains, Sihong Liu, Assaf Oshri, Lawrence H Sweet

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Article in Child abuse & neglect, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Joshua T McMainsDepartment of Psychology, University of Georgia, 125 Baldwin St, Athens, GA 30602, USA. Electronic address: jmcmains@uga.edu.
Sihong LiuDepartment of Human Development and Family Science, University of Georgia, 123 Dawson Hall, 305 Sanford Dr., Athens, GA 30602, USA. Electronic address: sihongl@stanford.edu.
Assaf OshriDepartment of Human Development and Family Science, University of Georgia, 123 Dawson Hall, 305 Sanford Dr., Athens, GA 30602, USA. Electronic address: oshri@uga.edu.
Lawrence H SweetDepartment of Psychology, University of Georgia, 125 Baldwin St, Athens, GA 30602, USA. Electronic address: sweet@uga.edu.

Funding

The influence of community and family protective processes on neurocognitive systems associated with early-onset drug use: An investigation of rural southern youthK01DA045219 · NIDA · UNIVERSITY OF GEORGIA · PI OSHRI, ASSAF · 2018 to 2022
$889k
NIDA NIH HHS K01 DA045219
6 · The paper itself

Abstract

BACKGROUND/

aimsThe link between child maltreatment (CM) and substance use (SU) in young adulthood is established. The sympathetic nervous system (SNS) division of the autonomic nervous system may mediate this link. However, less is known on the indirect link between CM and SU via SNS functioning. Due to individual variability in the link between SNS functioning and SU risk, we aimed to examine the moderating role of distress tolerance (DT).

methodsA longitudinal sample of 118 young adults (YAs) from a low socioeconomic status background were assessed twice (between 9 and 12 months apart). CM, DT, and galvanic skin response (GSR) stress reactivity were measured during the initial study visit, while SU was assessed at both timepoints. Stress reactivity was assessed by measuring the GSR reactivity during a stress task. We tested the indirect associations between CM and changes in SU problems via GSR stress reactivity, and the moderation effects of DT on these indirect associations. A mediation model in the structural equation modeling (SEM) framework was then followed by a moderated mediation model to analyze these data.

resultsYA's stress reactivity mediated the association between CM and alcohol use problems, and this indirect effect was weaker among YAs who had higher levels of DT. This pattern did not emerge with drug use problems.

conclusionsFindings suggest that intervention and prevention efforts for SU outcomes should consider incorporating strategies that increase at-risk individuals' levels of DT. Providing strategies to help individuals stem their stress reactivity may reduce their risk for alcohol use.

Indexed as

Autonomic Nervous SystemSubstance-Related DisordersAdolescentAdultAdult Survivors of Child AbuseAdverse Childhood ExperiencesChildChild AbuseFemaleGalvanic Skin ResponseHumansLongitudinal StudiesMaleMediation AnalysisPsychological DistressRisk FactorsChild maltreatmentDistress toleranceStress reactivitySubstance use

Identifiers

PMID39024782
PMCPMC11316649

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