Evidence map›Paper›PMID 39024259›Full record

ArticlePloS one2024

Lead exposure sources and public health investigations for children with elevated blood lead in England, 2014 to 2022.

Mona Dave, Araceli Busby, Lena Al Shammari, Neelam Iqbal, Louise Coole, Helen Bagnall, Helen Crabbe

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mona DaveUK Field Epidemiology Training Programme, UK Health Security Agency, London, United Kingdom.ORCID 0009-0001-5306-2403
Araceli BusbyNorth East and North Central London Health Protection Team, UK Health Security Agency, London, United Kingdom.
Lena Al ShammariNorth East and North Central London Health Protection Team, UK Health Security Agency, London, United Kingdom.
Neelam IqbalEnvironmental Epidemiology Group, Radiation Chemicals and Environmental Hazards Directorate, UK Health Security Agency, Oxfordshire, United Kingdom.
Louise CooleUK Field Epidemiology Training Programme, UK Health Security Agency, London, United Kingdom.
Helen BagnallField Service Midlands, Regions Directorate, UK Health Security Agency, Birmingham, United Kingdom.
Helen CrabbeEnvironmental Epidemiology Group, Radiation Chemicals and Environmental Hazards Directorate, UK Health Security Agency, Oxfordshire, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLead exposure at any concentration can adversely impact health, with children being more vulnerable to its effects. In England, children with an elevated blood lead concentration (BLC) are reported to Health Protection Teams (HPTs) for public health investigation. A detailed review of these cases has not yet been conducted.

objectivesThe objectives of this study were to describe the demographics, likely setting and sources of lead exposure, risk behaviours, public health investigations and outcomes for children aged <16 years with a BLC requiring public health action reported to HPTs between 2014-2022 in England.

methodsData were collected via a lookback questionnaire and a live enhanced surveillance questionnaire. Data were deduplicated, cleaned and results summarised as numbers and percentages using R studio. A thematic analysis was conducted on qualitative responses to a question relating to problems experienced during case investigation.

resultsThere were 340 cases in our study: the majority were aged 1-4 years old (53%) and male (69%). Ethnicity data was poorly recorded. A higher than expected proportion (31%) lived in the most deprived areas. Pica (76%) and learning difficulties (60%) were often present. Cases were primarily exposed to lead in the domestic setting (92%) with paint (43%) and soil (29%) the most common exposures. Most cases lived in rented accommodation (63%), with a higher proportion in social rentals (48%) than privately rented (37%). Case investigations were resource intensive and poor stakeholder engagement/response was most frequently identified as challenging by HPTs.

conclusionsLead exposure is harmful to children and requires public health and clinical management, which can be complex and challenging. Prevention of lead exposure in children should be the focus of intervention efforts. Outreach, engagement and preventative work should focus on both renters and homeowners. Collecting ethnicity data consistently may enable identification of more specific groups at increased risk of lead exposure in England.

Indexed as

Environmental ExposureLeadLead PoisoningPublic HealthAdolescentChildChild, PreschoolEnglandFemaleHumansInfantMaleSurveys and QuestionnairesLead

Identifiers

PMID39024259
PMCPMC11257228

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.