Evidence map›Paper›PMID 39023829›Full record

GuidelineClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2024

SEOM-GEMCAD-TTD clinical guideline for the diagnosis and treatment of gastric cancer (2023).

Fernando Rivera, Federico Longo, Marta Martín Richard, Paula Richart, Maria Alsina, Alberto Carmona, Ana Belén Custodio, Ana Fernández Montes, Javier Gallego, Tania Fleitas Kanonnikoff

Abstract readPractice Guideline
In one paragraph

Guideline in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. Observational
  5. Targetable pathways for drug repurposing in gastric cancer.World journal of gastroenterology · 2025
    Review
  6. Article
  7. Article
  8. SEOM 2023 clinical guidelines.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fernando RiveraMedical Oncology Department, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain. fernando.rivera@scsalud.es.ORCID http://orcid.org/0000-0001-8915-226X
Federico LongoMedical Oncology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.ORCID http://orcid.org/0000-0003-0902-2188
Marta Martín RichardMedical Oncology Department, ICO Duran i Reynals, Barcelona, Spain.
Paula RichartMedical Oncology Department, Hospital La Fe, Valencia, Spain.
Maria AlsinaMedical Oncology Department, Hospital Universitario de Navarra (HUN), Pamplona, Spain.ORCID http://orcid.org/0000-0003-4835-7159
Alberto CarmonaMedical Oncology Department, Hospital Morales Meseguer, Murcia, Spain.ORCID http://orcid.org/0000-0002-1930-9660
Ana Belén CustodioMedical Oncology Department, Hospital Universitario La Paz, Madrid, Spain.
Ana Fernández MontesMedical Oncology Department, Complexo Hospitalario Universitario de Ourense (CHUO), Ourense, Spain.ORCID http://orcid.org/0000-0003-4630-5830
Javier GallegoMedical Oncology Department, Hospital General Universitario de Elche, Alicante, Spain.
Tania Fleitas KanonnikoffMedical Oncology Department, Hospital Clínico Universitario de Valencia, INCLIVA, Valencia, Spain. tfleitask@gmail.com.ORCID http://orcid.org/0000-0002-2789-9082

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) is the fifth most common cancer worldwide with a varied geographic distribution and an aggressive behavior. In Spain, the incidence is lower and GC represents the tenth most frequent tumor and the seventh cause of cancer mortality. Molecular biology knowledge allowed to better profile patients for a personalized therapeutic approach. In the localized setting, the multidisciplinary team discussion is fundamental for planning the therapeutic approach. Endoscopic resection in very early stage, perioperative chemotherapy in locally advanced tumors, and chemoradiation + surgery + adjuvant immunotherapy for the GEJ are current standards. For the metastatic setting, biomarker profiling including Her2, PD-L1, MSS status is needed. Chemotherapy in combination with checkpoint inhibitors had improved the outcomes for patients with PD-L1 expression. Her2 positive patients should receive antiHer2 therapy added to chemotherapy. We describe the different evidences and recommendations based on the literature.

Indexed as

Stomach NeoplasmsBiomarkers, TumorErb-b2 Receptor Tyrosine KinasesHumansImmune Checkpoint InhibitorsImmunotherapyMedical OncologySpainBiomarkers, TumorErb-b2 Receptor Tyrosine KinasesImmune Checkpoint InhibitorsGastric cancerImmunotherapyPrecision medicineSupportive careTumor biology

Identifiers

PMID39023829
PMCPMC11467061

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.