Evidence map›Paper›PMID 39023828›Full record

ReviewJournal of assisted reproduction and genetics2024

Interrogating erectile dysfunction and evaluating novel therapeutic frontiers, with emphasis on stem cell strategies.

Tareeka Sonawane, Shivaji Kashte, Simran Khera, Ashutosh Bahulkar, Chennakesava Cuddapah, Sachin Kadam

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of assisted reproduction and genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tareeka SonawaneAmity Institute of Biotechnology, Amity University, Bhatan, Post-Somathne, Panvel, Mumbai, 410206, India.
Shivaji KashteCenter For Interdisciplinary Research, D Y Patil Education Society, Kasaba Bawada, Kolhapur, 416006, India.
Simran KheraAmity Institute of Biotechnology, Amity University, Bhatan, Post-Somathne, Panvel, Mumbai, 410206, India.
Ashutosh BahulkarDepartment of Obstetrics and Gynecology, Krishna Institute of Medical Sciences, Malkapur, Karad, Dist. Satara, Maharashtra , 415539, India.
Chennakesava CuddapahCurio Biotech Ltd, Rottenstrasse 5, 3930, Visp, Switzerland.
Sachin KadamSophisticated Analytical and Technical Help Institute, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, 110016, India. kadamsachin@gmail.com.ORCID http://orcid.org/0000-0002-9937-4736

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Male infertility arises from a complex interplay of factors affecting reproductive organs and various physiological pathways. Among these, erectile dysfunction (ED), a widespread global issue, plays a key role. While existing ED treatments address some aspects, achieving complete reversibility and avoiding side effects remains a challenge. In this context, stem cell therapy emerges as a promising, potentially transformative approach. Preliminary evidence from preclinical animal models and clinical trials highlights stem cell therapy's remarkable efficacy and effectiveness for ED. This novel strategy offers several advantages, including enhanced effectiveness and a reported absence of adverse side effects. This review delves into the causes of male infertility, with a particular focus on ED and its pathophysiology. We explore the current treatment landscape, highlighting therapy's existing strategies' limitations and stem cell therapy's unique potential. By examining relevant preclinical and clinical studies, we provide a comprehensive picture of this innovative approach and its promising future in restoring men's fertility and quality of life.

Indexed as

Erectile DysfunctionInfertility, MaleStem Cell TransplantationAnimalsHumansMaleQuality of LifeStem CellsErectile dysfunctionMale infertilityStem cellsStem cell therapy

Identifiers

PMID39023828
PMCPMC11339218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.