Evidence map›Paper›PMID 39023701›Full record

ReviewProbiotics and antimicrobial proteins2025

Pyocins and Beyond: Exploring the World of Bacteriocins in Pseudomonas aeruginosa.

Muhammad Suleman, Allah Rakha Yaseen, Shahbaz Ahmed, Zoha Khan, Asma Irshad, Afsah Pervaiz, Hafiza Hiba Rahman, Muteeba Azhar

Abstract readReview
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In one paragraph

Review in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Muhammad SulemanSchool of Biological Sciences, Faculty of Life Sciences, University of the Punjab, Lahore, 54590, Pakistan. msulemanmughal123@gmail.com.
Allah Rakha YaseenSchool of Biological Sciences, Faculty of Life Sciences, University of the Punjab, Lahore, 54590, Pakistan.
Shahbaz AhmedSchool of Biological Sciences, Faculty of Life Sciences, University of the Punjab, Lahore, 54590, Pakistan.
Zoha KhanSchool of Biochemistry and Biotechnology, University of the Punjab, Lahore, 54590, Pakistan.
Asma IrshadSchool of Biochemistry and Biotechnology, University of the Punjab, Lahore, 54590, Pakistan.
Afsah PervaizInstitute of Microbiology, University of Veterinary and Animal Sciences, Lahore, Pakistan.
Hafiza Hiba RahmanDepartment of Pathology, University of Veterinary and Animal Sciences, Lahore, Pakistan.
Muteeba AzharSchool of Biochemistry and Biotechnology, University of the Punjab, Lahore, 54590, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudomonas aeruginosa significantly induces health-associated infections in a variety of species other than humans. Over the years, the opportunistic pathogen has developed resistance against commonly used antibiotics. Since most P. aeruginosa strains are multi-drug resistant, regular antibiotic treatment of its infections is becoming a dire concern, shifting the global focus towards the development of alternate antimicrobial approaches. Pyocins are one of the most diverse antimicrobial peptide combinations produced by bacteria. They have potent antimicrobial properties, mainly against bacteria from the same phylogenetic group. P. aeruginosa, whether from clinical or environmental origins, produce several different pyocins that show inhibitory activity against other multi-drug-resistant strains of P. aeruginosa. They are, therefore, good candidates for alternate therapeutic antimicrobials because they have a unique mode of action that kills antibiotic-resistant bacteria by attacking their biofilms. Here, we review pseudomonas-derived antimicrobial pyocins with great therapeutic potential against multi-drug-resistant P. aeruginosa.

Indexed as

Anti-Bacterial AgentsBacteriocinsPseudomonas aeruginosaPyocinsBiofilmsDrug Resistance, Multiple, BacterialHumansPseudomonas InfectionsAnti-Bacterial AgentsBacteriocinsPyocinsAntimicrobial resistanceBacteriocinsPseudomonas aeruginosaPyocins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.