Evidence map›Paper›PMID 39023416›Full record

ArticleCurrent protocols2024

Expanded Antigen-Specific Elimination Assay to Measure Human CD8

David R Collins, Mpho J Olatotse, Zachary J Racenet, Umar Arshad, Elif Çakan, Gaurav D Gaiha, Kiera L Clayton, Bruce D Walker

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current protocols, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. CD8Nature · 2026
    Article
  2. CD8medRxiv : the preprint server for health sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David R CollinsRagon Institute of MGH, MIT & Harvard, Cambridge, Massachusetts.ORCID https://orcid.org/0000-0001-7903-346X
Mpho J OlatotseRagon Institute of MGH, MIT & Harvard, Cambridge, Massachusetts.
Zachary J RacenetRagon Institute of MGH, MIT & Harvard, Cambridge, Massachusetts.
Umar ArshadRagon Institute of MGH, MIT & Harvard, Cambridge, Massachusetts.
Elif ÇakanRagon Institute of MGH, MIT & Harvard, Cambridge, Massachusetts.
Gaurav D GaihaRagon Institute of MGH, MIT & Harvard, Cambridge, Massachusetts.
Kiera L ClaytonRagon Institute of MGH, MIT & Harvard, Cambridge, Massachusetts.
Bruce D WalkerRagon Institute of MGH, MIT & Harvard, Cambridge, Massachusetts.

Funding

Understanding and Reversing T Cell Dysfunction to Control and Eliminate Persistent HIV ReservoirsR01AI149704 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI WALKER, BRUCE D · 2020 to 2024
$2.1M
Modulating T Cell Activation to Combat HIV PersistenceDP2AI184606 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI David Randolph Collins · 2024 to 2026
$1.5M
Howard Hughes Medical InstituteNIAID NIH HHS DP2 AI184606NIAID NIH HHS L30 AI126472NIAID NIH HHS R01 AI149704NIH HHS L30 AI126472NIH HHS R01 AI149704
6 · The paper itself

Abstract

Durable cellular immunity against pathogens is dependent upon a coordinated recall response to antigen by memory CD8

Indexed as

CD8-Positive T-LymphocytesFlow CytometryAntigensCytotoxicity, ImmunologicHumansAntigenscytotoxicityepitope‐specificflow cytometryhuman CD8+ T cellsT cell memory

Identifiers

PMID39023416
PMCPMC11295945

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.