ArticleRadiology. Cardiothoracic imaging2024
Enabling Reliable Visual Detection of Chronic Myocardial Infarction with Native T1 Cardiac MRI Using Data-Driven Native Contrast Mapping.
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Article in Radiology. Cardiothoracic imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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11 authors.
Khalid YoussefFrom the Krannert Cardiovascular Research Center, Indiana University School of Medicine, IU Health Cardiovascular Institute, 1700 N Capitol Ave, E316, Indianapolis, IN 46202-1228 (K.Y., X.Z., G.Y., S.F.C., K.V., B.S., R.D.); University of California Los Angeles, Los Angeles, Calif (X.Z.); Zhongshan Hospital, Fudan University, Shanghai, China (Y.C.); Cedars-Sinai Medical Center, Los Angeles, Calif (H.J.Y.); Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada (A.H.); and Northern Ontario School of Medicine University, Sudbury, Canada (A.K.).ORCID 0000-0003-4429-367X
Xinheng ZhangFrom the Krannert Cardiovascular Research Center, Indiana University School of Medicine, IU Health Cardiovascular Institute, 1700 N Capitol Ave, E316, Indianapolis, IN 46202-1228 (K.Y., X.Z., G.Y., S.F.C., K.V., B.S., R.D.); University of California Los Angeles, Los Angeles, Calif (X.Z.); Zhongshan Hospital, Fudan University, Shanghai, China (Y.C.); Cedars-Sinai Medical Center, Los Angeles, Calif (H.J.Y.); Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada (A.H.); and Northern Ontario School of Medicine University, Sudbury, Canada (A.K.).
Ghazal YoosefianFrom the Krannert Cardiovascular Research Center, Indiana University School of Medicine, IU Health Cardiovascular Institute, 1700 N Capitol Ave, E316, Indianapolis, IN 46202-1228 (K.Y., X.Z., G.Y., S.F.C., K.V., B.S., R.D.); University of California Los Angeles, Los Angeles, Calif (X.Z.); Zhongshan Hospital, Fudan University, Shanghai, China (Y.C.); Cedars-Sinai Medical Center, Los Angeles, Calif (H.J.Y.); Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada (A.H.); and Northern Ontario School of Medicine University, Sudbury, Canada (A.K.).
Yinyin ChenFrom the Krannert Cardiovascular Research Center, Indiana University School of Medicine, IU Health Cardiovascular Institute, 1700 N Capitol Ave, E316, Indianapolis, IN 46202-1228 (K.Y., X.Z., G.Y., S.F.C., K.V., B.S., R.D.); University of California Los Angeles, Los Angeles, Calif (X.Z.); Zhongshan Hospital, Fudan University, Shanghai, China (Y.C.); Cedars-Sinai Medical Center, Los Angeles, Calif (H.J.Y.); Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada (A.H.); and Northern Ontario School of Medicine University, Sudbury, Canada (A.K.).
Shing Fai ChanFrom the Krannert Cardiovascular Research Center, Indiana University School of Medicine, IU Health Cardiovascular Institute, 1700 N Capitol Ave, E316, Indianapolis, IN 46202-1228 (K.Y., X.Z., G.Y., S.F.C., K.V., B.S., R.D.); University of California Los Angeles, Los Angeles, Calif (X.Z.); Zhongshan Hospital, Fudan University, Shanghai, China (Y.C.); Cedars-Sinai Medical Center, Los Angeles, Calif (H.J.Y.); Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada (A.H.); and Northern Ontario School of Medicine University, Sudbury, Canada (A.K.).
Hsin-Jung YangFrom the Krannert Cardiovascular Research Center, Indiana University School of Medicine, IU Health Cardiovascular Institute, 1700 N Capitol Ave, E316, Indianapolis, IN 46202-1228 (K.Y., X.Z., G.Y., S.F.C., K.V., B.S., R.D.); University of California Los Angeles, Los Angeles, Calif (X.Z.); Zhongshan Hospital, Fudan University, Shanghai, China (Y.C.); Cedars-Sinai Medical Center, Los Angeles, Calif (H.J.Y.); Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada (A.H.); and Northern Ontario School of Medicine University, Sudbury, Canada (A.K.).ORCID 0000-0001-9379-5495
Keyur VoraFrom the Krannert Cardiovascular Research Center, Indiana University School of Medicine, IU Health Cardiovascular Institute, 1700 N Capitol Ave, E316, Indianapolis, IN 46202-1228 (K.Y., X.Z., G.Y., S.F.C., K.V., B.S., R.D.); University of California Los Angeles, Los Angeles, Calif (X.Z.); Zhongshan Hospital, Fudan University, Shanghai, China (Y.C.); Cedars-Sinai Medical Center, Los Angeles, Calif (H.J.Y.); Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada (A.H.); and Northern Ontario School of Medicine University, Sudbury, Canada (A.K.).
Andrew HowarthFrom the Krannert Cardiovascular Research Center, Indiana University School of Medicine, IU Health Cardiovascular Institute, 1700 N Capitol Ave, E316, Indianapolis, IN 46202-1228 (K.Y., X.Z., G.Y., S.F.C., K.V., B.S., R.D.); University of California Los Angeles, Los Angeles, Calif (X.Z.); Zhongshan Hospital, Fudan University, Shanghai, China (Y.C.); Cedars-Sinai Medical Center, Los Angeles, Calif (H.J.Y.); Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada (A.H.); and Northern Ontario School of Medicine University, Sudbury, Canada (A.K.).
Andreas KumarFrom the Krannert Cardiovascular Research Center, Indiana University School of Medicine, IU Health Cardiovascular Institute, 1700 N Capitol Ave, E316, Indianapolis, IN 46202-1228 (K.Y., X.Z., G.Y., S.F.C., K.V., B.S., R.D.); University of California Los Angeles, Los Angeles, Calif (X.Z.); Zhongshan Hospital, Fudan University, Shanghai, China (Y.C.); Cedars-Sinai Medical Center, Los Angeles, Calif (H.J.Y.); Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada (A.H.); and Northern Ontario School of Medicine University, Sudbury, Canada (A.K.).
Behzad SharifFrom the Krannert Cardiovascular Research Center, Indiana University School of Medicine, IU Health Cardiovascular Institute, 1700 N Capitol Ave, E316, Indianapolis, IN 46202-1228 (K.Y., X.Z., G.Y., S.F.C., K.V., B.S., R.D.); University of California Los Angeles, Los Angeles, Calif (X.Z.); Zhongshan Hospital, Fudan University, Shanghai, China (Y.C.); Cedars-Sinai Medical Center, Los Angeles, Calif (H.J.Y.); Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada (A.H.); and Northern Ontario School of Medicine University, Sudbury, Canada (A.K.).ORCID 0000-0002-8945-8178
Rohan DharmakumarFrom the Krannert Cardiovascular Research Center, Indiana University School of Medicine, IU Health Cardiovascular Institute, 1700 N Capitol Ave, E316, Indianapolis, IN 46202-1228 (K.Y., X.Z., G.Y., S.F.C., K.V., B.S., R.D.); University of California Los Angeles, Los Angeles, Calif (X.Z.); Zhongshan Hospital, Fudan University, Shanghai, China (Y.C.); Cedars-Sinai Medical Center, Los Angeles, Calif (H.J.Y.); Libin Cardiovascular Institute of Alberta, University of Calgary, Alberta, Canada (A.H.); and Northern Ontario School of Medicine University, Sudbury, Canada (A.K.).
Funding
Developing a MRI-guided Disease-Modifying Therapy for Post Infarction Chronic Heart FailureR01HL133407 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI Rohan Dharmakumar · 2017 to 2026
$4.9MAn Accurate Non-Contrast-Enhanced Cardiac MRI Method for Imaging Chronic Myocardial Infarctions: Technical Developments to Rapid Clinical ValidationR01HL136578 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI LI, DEBIAO · 2017 to 2020
$3.4MMechanistic Insights to A Translatable Therapy for Acute Reperfused Hemorrhagic Myocardial InfarctionsR01HL147133 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI DHARMAKUMAR, ROHAN, FRANCIS, JOSEPH · 2020 to 2023
$3.2MNoninvasive Testing of Coronary Microvascular Reactivity Using High-resolution Free-breathing MRIR01HL153430 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI SHARIF, BEHZAD · 2020 to 2024
$2.9MNHLBI NIH HHS R01 HL133407NHLBI NIH HHS R01 HL136578NHLBI NIH HHS R01 HL147133NHLBI NIH HHS R01 HL153430
Abstract
Purpose To investigate whether infarct-to-remote myocardial contrast can be optimized by replacing generic fitting algorithms used to obtain native T1 maps with a data-driven machine learning pixel-wise approach in chronic reperfused infarct in a canine model. Materials and Methods A controlled large animal model (24 canines, equal male and female animals) of chronic myocardial infarction with histologic evidence of heterogeneous infarct tissue composition was studied. Unsupervised clustering techniques using self-organizing maps and
Indexed as
Contrast MediaMyocardial InfarctionAlgorithmsAnimalsChronic DiseaseDisease Models, AnimalDogsFemaleMagnetic Resonance ImagingMaleReproducibility of ResultsContrast MediaCardiac MRIChronic Myocardial InfarctionData-Driven Native Contrast Mapping
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.