Evidence map›Paper›PMID 39023271›Full record

ArticleInfection and immunity2024

Virus-like particles displaying the mature C-terminal domain of filamentous hemagglutinin are immunogenic and protective against

Gage M Pyles, Annalisa B Huckaby, Maria de la Paz Gutierrez, William T Witt, Margalida Mateu-Borrás, Spencer R Dublin, Carleena Rocuskie-Marker, Bethany N Sesti, Kerrington Peasak, Graham J Bitzer and 8 more

Abstract read
In one paragraph

Article in Infection and immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Gage M PylesDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.ORCID 0000-0002-5782-5658
Annalisa B HuckabyDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Maria de la Paz GutierrezDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
William T WittDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Margalida Mateu-BorrásDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Spencer R DublinDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Carleena Rocuskie-MarkerDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Bethany N SestiDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Kerrington PeasakDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Graham J BitzerDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Nathaniel RaderDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Kelly L WeaverDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Dylan T BoehmDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Nicholas FitzgeraldDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Joshua ChapmanDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Samuel UlicnyDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
F Heath DamronDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.ORCID 0000-0002-3140-402X
Mariette BarbierDepartment of Microbiology, Immunology and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.ORCID 0000-0002-3250-3636

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Anne Courtney DeVries · 2012 to 2026
$81.0M
Development of mRNA-platform vaccinesR01AI153250 · NIAID · WEST VIRGINIA UNIVERSITY · PI DAMRON, FREDRICK HEATH · 2021 to 2025
$4.1M
Development of mucosal vaccines to protect against pertussisR01AI137155 · NIAID · WEST VIRGINIA UNIVERSITY · PI DAMRON, FREDRICK HEATH · 2019 to 2023
$2.9M
Vaccine Development Against Bacterial Pathogens Based on iron Acquisition ProteinsR01AI141671 · NIAID · WEST VIRGINIA UNIVERSITY · PI BARBIER, MARIETTE · 2019 to 2023
$2.5M
HHS | National Institutes of Health (NIH) R01AI141671NIAID NIH HHS R01 AI137155NIAID NIH HHS R01 AI141671NIAID NIH HHS R01 AI153250NIGMS NIH HHS U54 GM104942West Virginia Higher Education Policy Commission (WVHEPC) HEPC.dsr.18.6
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adhesins, BacterialAntibodies, BacterialBordetella pertussisPertussis VaccineVaccines, Virus-Like ParticleWhooping CoughAnimalsFemaleMiceMice, Inbred BALB CRespiratory Tract InfectionsVirulence Factors, BordetellaAdhesins, BacterialAntibodies, Bacterialfilamentous hemagglutinin adhesin, Bordetella pertussisPertussis VaccineVaccines, Virus-Like ParticleVirulence Factors, Bordetellabacterial challengeBordetella pertussisDTaPFHApertussispertussis mouse modelpertussis toxinvaccine evaluationvaccinesVLPwhooping cough

Identifiers

PMID39023271
PMCPMC11320929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.