Evidence map›Paper›PMID 39023087›Full record

ArticleClinical transplantation2024

Medical Distrust Among Kidney Transplant Candidates.

Valerie L Thompson, Yiting Li, Yi Liu, Jingyao Hong, Swati Sharma, Garyn Metoyer, Maya N Clark-Cutaia, Tanjala S Purnell, Deidra C Crews, Dorry L Segev and 1 more

Abstract read
In one paragraph

Article in Clinical transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Valerie L ThompsonDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0001-6502-8600
Yiting LiDepartment of Surgery, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0000-0001-6279-5740
Yi LiuDepartment of Surgery, New York University Grossman School of Medicine, New York, New York, USA.
Jingyao HongDepartment of Surgery, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0000-0002-8156-1306
Swati SharmaDepartment of Surgery, New York University Grossman School of Medicine, New York, New York, USA.
Garyn MetoyerDepartment of Surgery, New York University Grossman School of Medicine, New York, New York, USA.
Maya N Clark-CutaiaRory Meyers College of Nursing, New York University, New York, New York, USA.
Tanjala S PurnellDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-8661-7911
Deidra C CrewsDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Dorry L SegevDepartment of Surgery, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0000-0002-1924-4801
Mara McAdams-DeMarcoDepartment of Surgery, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0000-0003-3013-925X

Funding

Structural Racism, Resilience, and Premature Cognitive Aging in End-Stage Renal Disease - Revision - 5R01AG077888 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Mara A. McAdams DeMarco · 2022 to 2026
$4.4M
Kidney transplantation in older, frail and cognitively impaired adults with ESRD: Balancing utility vs. justiceR01AG055781 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MCADAMS DEMARCO, MARA A. · 2017 to 2021
$4.2M
Hemodialysis-based interventions to preserve cognitive functionR01DK114074 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MCADAMS DEMARCO, MARA A. · 2018 to 2022
$3.9M
Developing personalized immunosuppression for older kidney transplant recipientsR01DK120518 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MCADAMS DEMARCO, MARA A. · 2019 to 2022
$2.7M
Patient Oriented Research in Solid Organ TransplantationK24AI144954 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SEGEV, DORRY L. · 2020 to 2024
$956k
Impact of climate change on cognitive and physical aging of older kidney transplant recipientsK02AG076883 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Mara A. McAdams DeMarco · 2023 to 2026
$728k
National Institute of Allergy and Infectious DiseasesNIAID NIH HHS K24 AI144954NIA NIH HHS K02 AG076883NIA NIH HHS R01 AG055781NIA NIH HHS R01 AG077888NIDDK NIH HHS R01 DK114074NIDDK NIH HHS R01 DK120518
6 · The paper itself

Abstract

backgroundMedical distrust may hinder kidney transplantation (KT) access. Among KT candidates evaluated for waitlisting, we identified factors associated with high distrust levels and quantified their association with waitlisting.

methodsAmong 812 candidates (2018-2023), we assessed distrust using the Revised Health Care System Distrust Scale across composite, competence, and values subscales. We used linear regression to quantify the associations between candidate and neighborhood-level factors and distrust scores. We used Cox models to quantify the associations between distrust scores and waitlisting.

resultsAt KT evaluation, candidates who were aged 35-49 years (difference = 1.97, 95% CI: 0.78-3.16), female (difference = 1.10, 95% CI: 0.23-1.97), and Black (difference = 1.47, 95% CI: 0.47-2.47) were more likely to report higher composite distrust score. For subscales, candidates aged 35-49 were more likely to have higher competence distrust score (difference = 1.14, 95% CI: 0.59-1.68) and values distrust score (difference = 0.83, 95% CI: 0.05-1.61). Race/ethnicity (Black, difference = 1.42, 95% CI: 0.76-2.07; Hispanic, difference = 1.52, 95% CI: 0.35-2.69) was only associated with higher values distrust scores. Female candidates reporting higher rescaled values distrust scores (each one point) had a lower chance of waitlisting (aHR = 0.78, 95% CI: 0.63-0.98), whereas this association was not observed among males. Similarly, among non-White candidates, each 1-point increase in both rescaled composite (aHR = 0.87, 95% CI: 0.77-0.99) and values (aHR = 0.82, 95% CI: 0.68-0.99) distrust scores was associated with a lower chance of waitlisting, while there was no association among White candidates.

conclusionFemale, younger, and non-White candidates reported higher distrust scores. Values distrust may contribute to the long-standing racial/ethnic and gender disparities in access to KT. Implementing tailored strategies to reduce distrust in transplant care may improve KT access for groups that experience persistent disparities.

Indexed as

Kidney TransplantationTrustWaiting ListsAdultFemaleFollow-Up StudiesHumansKidney Failure, ChronicMaleMiddle AgedPrognosisdisparitieskidney transplantkidney transplant evaluationmedical distrust

Identifiers

PMID39023087
PMCPMC11259129

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.