Evidence map›Paper›PMID 39022794›Full record

ArticleAmerican journal of clinical and experimental immunology2024

Analysis of immune cells and risk factors related to lower limb deep vein thrombosis in patients with cerebral infarction.

Feng-Dan Hu, Yun Miao, Bo Yu, Xiao-Zhen Deng, Ran Sun, Jin Qian, Hai-Xin Yuan

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Article in American journal of clinical and experimental immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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7 authors.

Feng-Dan HuShanghai Fifth Rehabilitation Hospital Shanghai 201600, China.
Yun MiaoShanghai First People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai 201600, China.
Bo YuShanghai First People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai 201600, China.
Xiao-Zhen DengShanghai Fifth Rehabilitation Hospital Shanghai 201600, China.
Ran SunShanghai First People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai 201600, China.
Jin QianShanghai Fifth Rehabilitation Hospital Shanghai 201600, China.
Hai-Xin YuanShanghai Fifth Rehabilitation Hospital Shanghai 201600, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the characteristics of hematologic indicators and related risk factors of lower extremity deep vein thrombosis (LDVT) in patients with cerebral infarction.

methodsThis study retrospectively analyzed data from 174 patients with cerebral infarction admitted to The Rehabilitation Department of Shanghai Fifth Rehabilitation Hospital and Shanghai First People's Hospital from June 2022 to June 2023. Based on the results of lower limb venous color Doppler ultrasound examinations, patients were divided into two groups: the LDVT group (35 cases) and the non-LDVT group (139 cases). We compared the clinical data and hematologic indicators (D-dimer value, fibrinogen, white blood cells, platelets, uric acid, creatinine, etc.) of the two groups to identify the risk factors of cerebral infarction complicated with LDVT.

resultsStatistical analysis revealed that the D-dimer values of the LDVT group were significantly (P<0.05) higher than those of the non-LDVT group. The uric acid value of the LDVT group was significantly lower than that of the non-LDVT group, with statistical significance (P<0.05). The Brunnstrom staging in the LDVT group was significantly different from that in the non-LDVT group (P<0.05). Meanwhile, binary logistic regression analysis showed that LDVT complicated with cerebral infarction was associated with D-dimer level [OR=1.302, 95% CI (1.077, 1.575)], uric acid level [OR=0.995, 95% CI (0.990, 1.000)], and Brunnstrom staging [OR=3.005, 95% CI (1.312, 6.880)].

conclusionD-dimer value, uric acid value, and Brunnstrom stage I to II are closely related to the occurrence of LDVT in patients with cerebral infarction. High D-dimer value, low uric acid value, and Brunnstrom stage I to II are independent risk factors for LDVT in cerebral infarction. Early assessment of D-dimer value, uric acid value, and Brunnstrom stage of cerebral infarction should be considered in clinical practice.

Indexed as

blood indicatorsCerebral infarctiondeep vein thrombosislower limbs

Identifiers

PMID39022794
PMCPMC11249860

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