Evidence map›Paper›PMID 39022778›Full record

ArticleIJTLD open2024

Disability, comorbidities and risk determinants at end of TB treatment in Kenya, Uganda, Zambia and Zimbabwe.

Kenya, Uganda, Zambia, and Zimbabwe TB Disability Study Group (members listed here in alphabetical order):, S A Adakun, F M Banda, A Bloom, M Bochnowicz, J Chakaya, A Chansa, H Chiguvare, R Chimzizi, C Colvin and 24 more

Abstract read
In one paragraph

Article in IJTLD open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Kenya, Uganda, Zambia, and Zimbabwe TB Disability Study Group (members listed here in alphabetical order):
S A AdakunMulago National Referral Hospital, Kampala, Uganda.
F M BandaUniversity Teaching Hospital, Ministry of Health, Lusaka, Zambia.
A BloomCredence, Contractor for USAID Health Training, Advisory, and Support Contract (GHTASC), Washington DC, USA.
M BochnowiczCredence, Contractor for USAID Health Training, Advisory, and Support Contract (GHTASC), Washington DC, USA.
J ChakayaDepartment of Medicine, Therapeutics, Dermatology and Psychiatry Kenyatta University, Nairobi.
A ChansaNdola Teaching Hospital, Ministry of Health, Ndola, Zambia.
H ChiguvareUnited States Agency for International Development (USAID), Harare, Zimbabwe.
R ChimziziMinistry of Health, USAID Long-term Exceptional Technical Assistance Project, Genesis, Lusaka, Zambia.
C ColvinUnited States Agency for International Development (USAID), Harare, Zimbabwe.
J P DongoInternational Union Against Tuberculosis and Lung Disease (The Union) Uganda Office, Kampala, Uganda.
A DurenaUnited States Agency for International Development (USAID), Harare, Zimbabwe.
C DuriDirectorate of Health Services, Harare City Council, Harare, Zimbabwe.
R EdmundUnited States Agency for International Development (USAID), Harare, Zimbabwe.
A D HarriesThe Union, Paris, France.
I KathureMinistry of Health, Division of National TB, Leprosy and Lung Disease Programme, Nairobi, Kenya.
F N KavengaMinistry of Health and Child Care, AIDS and TB Department, Harare, Zimbabwe.
Y LinThe Union, Paris, France.
H LuzzeNational Tuberculosis and Leprosy Programme, Ministry of Health, Kampala, Uganda.
I MbithiRespiratory Society of Kenya, Nairobi, Kenya.
M MputuNational Tuberculosis Programme, Ministry of Health/USAID TBLON, Lusaka; Zambia.
A MubangaNational Tuberculosis Programme, Ministry of Health/USAID TBLON, Lusaka; Zambia.
D NairThe Union, Paris, France.
M NgwenyaMinistry of Health and Child Care, AIDS and TB Department, Harare, Zimbabwe.
B OkotuMinistry of Health, Division of National TB, Leprosy and Lung Disease Programme, Nairobi, Kenya.
P OwitiUSAID, Health, Population and Nutrition Office, Kenya and East Africa, Nairobi.
A OwuorKenyatta National Hospital, Nairobi, Kenya.
P ThekkurThe Union, Paris, France.
C TimireThe Union, Paris, France.
S TuryahabweNational Tuberculosis and Leprosy Programme, Ministry of Health, Kampala, Uganda.
E TweyongyereNational Tuberculosis and Leprosy Programme, Ministry of Health, Kampala, Uganda.
M YaDiulUSAID, Washington DC, USA.
R ZachariahUNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR), World Health Organization, Geneva, Switzerland.
K ZimbaUSAID, Lusaka, Zambia.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundWe examined the feasibility of assessing and referring adults successfully completing TB treatment for comorbidities, risk determinants and disability in health facilities in Kenya, Uganda, Zambia and Zimbabwe.

methodsThis was a cross-sectional study within national TB programmes.

resultsHealth workers assessed 1,063 patients (78% of eligible) in a median of 22 min [IQR 16-35] and found it useful and feasible to accomplish in addition to other responsibilities. For comorbidities, 476 (44%) had HIV co-infection, 172 (16%) had high blood pressure (newly detected in 124), 43 (4%) had mental health disorders (newly detected in 33) and 36 (3%) had diabetes mellitus. The most common risk determinants were 'probable alcohol dependence' (15%) and malnutrition (14%). Disability, defined as walking <400 m in 6 min, was found in 151/882 (17%). Overall, 763 (72%) patients had at least one comorbidity, risk determinant and/or disability. At least two-thirds of eligible patients were referred for care, although 80% of those with disability needed referral outside their original health facility.

conclusionsSeven in 10 patients completing TB treatment had at least one comorbidity, risk determinant and/or disability. This emphasises the need for offering early patient-centred care, including pulmonary rehabilitation, to improve quality of life, reduce TB recurrence and increase long-term survival.

Indexed as

Real-time operational researchSORT ITTB-associated disabilityTB-associated lung diseaseUniversal health coverage

Identifiers

PMID39022778
PMCPMC11249599

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.