ArticlePostepy w kardiologii interwencyjnej = Advances in interventional cardiology2024
A multi-center study of the MicroNET-covered stent in consecutive patients with acute carotid-related stroke: SAFEGUARD-STROKE.
Article in Postepy w kardiologii interwencyjnej = Advances in interventional cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05195658 (Acute Stroke of CArotid Artery Bifurcation Origin Treated With Use oF The MicronEt-covered CGUARD STent Under TRansient FlOw Reversal LinKed With Thrombus REtrieval), which is not on this map. Cited by 8 papers.
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Acute Stroke of CArotid Artery Bifurcation Origin Treated With Use oF The MicronEt-covered CGUARD STent Under TRansient FlOw Reversal LinKed With Thrombus REtrieval: SAFEGUARD-STROKE Study
Who cites it
8 citing papers in PubMed.
- Plaque Prolapse in Carotid Artery Stenting: Mechanisms, Imaging and Device-Based Prevention.Medicina (Kaunas, Lithuania) · 2026Review
- CREST-2 findings are unchanged using an aggregated control group for the CAS and CEA trial.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2026Article
- Endovascular treatment strategies in highly-calcified carotid stenoses.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2026Article
- The Effect of Lesion Length on Doppler Velocities Used Routinely to Determine Carotid Stenosis Cross-Sectional Severity.Diagnostics (Basel, Switzerland) · 2025Article
- MicroNET-covered stent 'sandwich' technique to seal carotid artery perforation in a highly-calcific lesion.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2024Article
- Endovascular resolution of MicroNET-covered stent inadvertent implantation from the external to common carotid artery.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2024Article
- Commentary: A multi-center study of the MicroNET-covered stent in consecutive patients with acute carotid-related stroke: SAFEGUARD-STROKE.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2024Article
- MicroNET-covered stent (CGuard) routine use in acute carotid-related stroke - SAFEGUARD-STROKE Study: response to the Buffalo Group commentary.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2024Article
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Authors and funding
25 authors.
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Abstract
Introduction: Acute carotid-related stroke (CRS), with its large thrombo-embolic load and large volume of affected brain tissue, poses significant management challenges. First generation (single-layer) carotid stents fail to insulate the athero-thrombotic material; thus they are often non-optimized (increasing thrombosis risk), yet their use is associated with a significant (20-30%) risk of new cerebral embolism. Aim: To evaluate, in a multi-center multi-specialty investigator-initiated study, outcomes of the MicroNET-covered (cell area ≈ 0.02-0.03 mm Material and methods: Seventy-five patients (age 40-89 years, 26.7% women) were enrolled in 7 interventional stroke centers. Results: The median Alberta Stroke Program Early CT Score (ASPECTS) was 9 (6-10). Study stent use was 100% (no other stent types implanted); retrograde strategy predominated (69.2%) in tandem lesions. Technical success was 100%. Post-dilatation balloon diameter was 4.0 to 8.0 mm. 89% of patients achieved final modified Thrombolysis in Cerebral Infarction (mTICI) 2b-c/3. Glycoprotein IIb/IIIa inhibitor use as intraarterial (IA) bolus + intravenous (IV) infusion was an independent predictor of symptomatic intracranial hemorrhage (OR = 13.9, 95% CI: 5.1-84.5, Conclusions: This largest to-date study of the MicroNET-covered stent in consecutive CRS patients demonstrated a high acute angiographic success rate, high 90-day patency and favorable clinical outcomes despite variability in procedural strategies and pharmacotherapy (SAFEGUARD-STROKE NCT05195658).
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