Evidence map›Paper›PMID 39022664›Full record

ArticleBJUI compass2024

Understanding symptom contribution to sex inequality in bladder and renal cancer stage at diagnosis.

Yin Zhou, Georgios Lyratzopoulos, Prabhakar Rajan, Fiona M Walter, Jianhua Wu

Erratum issuedAbstract read
In one paragraph

Article in BJUI compass, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Erratum.BJUI compass · 2024
    Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Yin ZhouWolfson Institute of Population Health Queen Mary University of London London UK.ORCID https://orcid.org/0000-0002-8815-1457
Georgios LyratzopoulosInstitute of Epidemiology and Health Care University College London London UK.
Prabhakar RajanBarts Cancer Institute, Cancer Research UK City of London Centre Queen Mary University of London London UK.ORCID https://orcid.org/0000-0001-8064-9878
Fiona M WalterWolfson Institute of Population Health Queen Mary University of London London UK.
Jianhua WuWolfson Institute of Population Health Queen Mary University of London London UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Understanding sex-specific factors contributing to advanced-stage diagnosis can guide interventions to reduce sex inequality in patients with urological cancers. Method: We used linked primary care and cancer registry data to examine associations between symptoms and advanced-stage in 1151 bladder cancer and 440 renal cancer patients diagnosed between January 2012 and December 2015 in England. We performed logistic regression, adjusting for sex, age, deprivation and routes to diagnosis, including interaction terms between symptoms and sex and symptoms and age. Results: Female sex (OR vs. men 1.89 [1.28-2.79]; Conclusion: Non-haematuria symptoms are associated with higher risk of advanced-stage bladder cancer. Greater risk of advanced-stage bladder cancer in women may reflect biological differences in haematuria onset and sex differences during diagnostic process. Identifying higher risk women with haematuria may reduce sex inequalities in bladder cancer outcomes.

Indexed as

bladder cancercancer stageearly diagnosisrenal cancersex inequalitysymptomatic presentation

Identifiers

PMID39022664
PMCPMC11249815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.