Evidence map›Paper›PMID 39022659›Full record

ReviewBJUI compass2024

Effect of preoperative alpha-blockers on ureteroscopy outcomes: A meta-analysis of randomised trials.

Naeem Bhojani, Ben H Chew, Samir Bhattacharyya, Amy E Krambeck, Khurshid R Ghani, Larry E Miller

Erratum issuedAbstract readReview
In one paragraph

Review in BJUI compass, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Impact of Preoperative Silodosin on Ureteroscopy Outcomes for Ureterolithiasis: A Systematic Review and Meta-Analysis.International braz j urol : official journal of the Brazilian Society of Urology
    Pooled it
  2. Review
  3. Erratum.BJUI compass · 2024
    Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Naeem BhojaniDivision of Urology Centre Hospitalier de l'Université de Montréal, Montréal Québec Canada.ORCID https://orcid.org/0000-0003-2679-2635
Ben H ChewDepartment of Urologic Sciences University of British Columbia Vancouver BC Canada.ORCID https://orcid.org/0000-0002-5315-0710
Samir BhattacharyyaHealth Economics and Market Access Boston Scientific Marlborough Massachusetts USA.
Amy E KrambeckDepartment of Urology Northwestern University School of Medicine Chicago Illinois USA.
Khurshid R GhaniDepartment of Urology University of Michigan Medical School Ann Arbor Michigan USA.ORCID https://orcid.org/0000-0002-6089-0733
Larry E MillerDepartment of Biostatistics Miller Scientific Johnson City Tennessee USA.ORCID https://orcid.org/0000-0003-1594-1885

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This work aims to determine the efficacy and safety of preoperative alpha-blocker therapy on ureteroscopy (URS) outcomes. Methods: In this systematic review and meta-analysis of randomised trials of URS with or without preoperative alpha-blocker therapy, outcomes included the need for ureteral dilatation, stone access failure, procedure time, residual stone rate, hospital stay, and complications. Residual stone rates were reported with and without adjustments for spontaneous stone passage, medication noncompliance, or adverse events leading to patient withdrawal. Data were analysed using random-effects meta-analysis and meta-regression. Certainty of evidence was assessed using the GRADE criteria. Results: Among 15 randomised trials with 1653 patients, URS was effective and safe with a stone-free rate of 81.2% and rare (2.3%) serious complications. The addition of preoperative alpha-blockers reduced the need for ureteral dilatation (risk ratio [RR] = 0.48; 95% CI = 0.30 to 0.75; Conclusion: While URS is an effective and safe treatment for stone disease, preoperative alpha-blocker therapy is well tolerated and can further improve patient outcomes.

Indexed as

alpha‐blockerkidney stonesilodosintamsulosinureteralureteroscopy

Identifiers

PMID39022659
PMCPMC11249831

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.