ArticleFrontiers in cardiovascular medicine2024
A matter of sex-persistent predictive value of MECKI score prognostic power in men and women with heart failure and reduced ejection fraction: a multicenter study.
Article in Frontiers in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed.
- Beyond the slope: prognostic utility of the VE/VCOOpen heart · 2026Article
- Influence of patient sex on clinical decision-making in acute heart failure: a risk-adjusted analysis using the MEESSI-AHF score.Internal and emergency medicine · 2026Article
- MECKI score thresholds for heart transplantation referral of ambulatory heart failure patients.ESC heart failure · 2026Article
- Clinical and Prognostic Impact of Hemodynamic Gain Index and Heart Hemodynamic Reserve in Heart Failure with Reduced and Mildly Reduced Ejection Fraction: A Multicenter Study.Diagnostics (Basel, Switzerland) · 2025Article
- Prognostic significance of early stage aortic valve disease development in heart failure: insights from the MECKI score cohort.European heart journal open · 2025Article
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46 authors.
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Abstract
Background: A sex-based evaluation of prognosis in heart failure (HF) is lacking. Methods and results: We analyzed the Metabolic Exercise test data combined with Cardiac and Kidney Indexes (MECKI) score registry, which includes HF with reduced ejection fraction (HFrEF) patients. A cross-validation procedure was performed to estimate weights separately for men and women of all MECKI score parameters: left ventricular ejection fraction (LVEF), hemoglobin, kidney function assessed by Modification of Diet in Renal Disease, blood sodium level, ventilation vs. carbon dioxide production slope, and peak oxygen consumption (peakVO Conclusions: S-MECKI, i.e., the recalibrated MECKI according to sex-specific differences, constitutes a further step in the prognostic assessment of patients with severe HFrEF.
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