Evidence map›Paper›PMID 39022200›Full record

ReviewEuroasian journal of hepato-gastroenterology

Multidisciplinary Consensus for Rationalizing the Use of Acid Suppressants in Children and Adults: CONFOR.

Ram Y Prabhoo, Uday A Pai, Arun Wadhwa, Bhanu V Pillai, Chris D'souza, Manav Wadhawan, Manish Bhatnagar, Meena R Prabhoo, Sadanand Shetty, Venkatesh P Seshadri and 3 more

Abstract readReview
In one paragraph

Review in Euroasian journal of hepato-gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ram Y PrabhooDepartment of Orthopedics, Mukund Hospital, Mumbai, Maharashtra, India.
Uday A PaiDepartment of Pediatrics, Sai Kutti Clinic, Mumbai, Maharashtra, India.
Arun WadhwaDepartment of Pediatrics, Arun Wadhwa Clinic, New Delhi, India.
Bhanu V PillaiDepartment of Pediatric Gastroenterology, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Chris D'souzaDepartment of ENT, Holy Family Hospital, Mumbai, Maharashtra, India.
Manav WadhawanDepartment of Hepatology and Liver Transplant, BLK-Max Super Speciality Hospital, Delhi, India.
Manish BhatnagarDepartment of Gastroenterology, Orchid Mediservices, Ahmedabad, Gujarat, India.
Meena R PrabhooDepartment of Gynecology, Mukund Hospital, Mumbai, Maharashtra, India.
Sadanand ShettyDepartment of Cardiology, Somaiya Super Specialty Institute, Mumbai, Maharashtra, India.
Venkatesh P SeshadriDepartment of Gastroenterology, Apollo Hospital, Chennai, Tamil Nadu, India.
Shrish BhatnagarDepartment of Pediatric Gastroenterology, Era's Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India.
Subhash C ManchandaDepartment of Cardiology, Sir Ganga Ram Hospital, New Delhi, India.
Vijay KherDepartment of Nephrology and Transplant Medicine, Epitome Kidney and Urology Institute, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of acid suppression therapy (AST) is a common approach for managing a wide spectrum of acid peptic disorders. Histamine type 2-receptor antagonists (H2RAs) and proton pump inhibitors (PPIs) are the most widely prescribed AST in routine clinical practice. However, an exponential surge in the prescriptions of PPIs, such as Omeprazole, Esomeprazole, Pantoprazole, Lansoprazole in recent years and their associated adverse effects have raised concern about their inappropriate and overuse, both in children and adults. To address these issues, a three-step modified Delphi polling process was employed to establish best practice consensus statements for rationalizing the use of acid suppressants. A multidisciplinary expert panel of 13 health professionals across medical specialties, including gastroenterologists, hepatologists, pediatric gastroenterologists, pediatricians, otolaryngologists, cardiologists, nephrologists, gynecologist and orthopedists actively contributed to this collaborative process of consensus development. The expert panel proposed 21 consensus statements providing best practice points on the general use and safety of acid suppressants based on a comprehensive review of scientific literature and clinical expertise. The panel also collaboratively developed a PPI deprescribing algorithm. Altogether, this consensus paper offers evidence-based recommendations and guidance for the rational use of acid suppressants with a blueprint for deprescribing PPIs. This consensus paper contributes to aiding primary care practitioners in improving patient outcomes and minimizing healthcare costs. Additionally, it enhances patient safety and curtail inappropriate usage. How to cite this article: Prabhoo RY, Pai UA, Wadhwa A,

Indexed as

DeprescribingGastrointestinalH2RAsProton pump inhibitorsRanitidineSide effects

Identifiers

PMID39022200
PMCPMC11249898

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.