Evidence map›Paper›PMID 39022129›Full record

ArticleGenes & diseases2024

PDCD2 as a prognostic biomarker in glioma correlates with malignant phenotype.

Fengsheng Dai, Yixiao Yuan, Jiaqi Hao, Xing Cheng, Xiangyi Zhou, Li Zhou, Rui Tian, Yi Zhao, Tingxiu Xiang

Abstract read
In one paragraph

Article in Genes & diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fengsheng DaiDepartment of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Yixiao YuanDepartment of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Jiaqi HaoDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
Xing ChengDepartment of Neuro-Oncology, Chongqing University Cancer Hospital, Chongqing 400030, China.
Xiangyi ZhouDepartment of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Li ZhouChongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing 400030, China.
Rui TianChongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing 400030, China.
Yi ZhaoChongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing 400030, China.
Tingxiu XiangDepartment of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Programmed cell death 2 (PDCD2) is related to cancer progression and chemotherapy sensitivity. The role of PDCD2 in solid cancers (excluding hematopoietic malignancies) and their diagnosis and prognosis remains unclear. The TCGA, CGGA, GEPIA, cBioPortal, and GTEx databases were analyzed for expression, prognostic value, and genetic modifications of PDCD2 in cancer patients. Functional enrichment analysis, CCK8, colony formation assay, transwell assay, and xenograft tumor model were undertaken to study the PDCD2's biological function in glioma (GBMLGG). The

Indexed as

BiomarkerGliomaProgrammed cell death 2ProgressionSolid cancer

Identifiers

PMID39022129
PMCPMC11252777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.