Evidence map›Paper›PMID 39021958›Full record

ArticleHeliyon2024

Elucidating the mechano-molecular dynamics of TRAP activity using CRISPR/Cas9 mediated fluorescent reporter mice.

Dilara Yılmaz, Francisco C Marques, Yannick Fischer, Sandra Zimmermann, Gaonhae Hwang, Penny R Atkins, Neashan Mathavan, Amit Singh, Pedro P C de Souza, Gisela A Kuhn and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dilara YılmazInstitute for Biomechanics, ETH Zürich, Zürich, Switzerland.
Francisco C MarquesInstitute for Biomechanics, ETH Zürich, Zürich, Switzerland.
Yannick FischerInstitute for Biomechanics, ETH Zürich, Zürich, Switzerland.
Sandra ZimmermannInstitute for Biomechanics, ETH Zürich, Zürich, Switzerland.
Gaonhae HwangInstitute for Biomechanics, ETH Zürich, Zürich, Switzerland.
Penny R AtkinsInstitute for Biomechanics, ETH Zürich, Zürich, Switzerland.
Neashan MathavanInstitute for Biomechanics, ETH Zürich, Zürich, Switzerland.
Amit SinghInstitute for Biomechanics, ETH Zürich, Zürich, Switzerland.
Pedro P C de SouzaInstitute for Biomechanics, ETH Zürich, Zürich, Switzerland.
Gisela A KuhnInstitute for Biomechanics, ETH Zürich, Zürich, Switzerland.
Esther WehrleInstitute for Biomechanics, ETH Zürich, Zürich, Switzerland.
Ralph MüllerInstitute for Biomechanics, ETH Zürich, Zürich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoclasts are essential for bone remodeling by adapting their resorptive activity in response to their mechanical

Indexed as

Bone remodelingCRISPR/Cas9 mediated reporter miceFluorescent osteoclasts and osteoblastsIn vivo loadingMechanosensitivityMicro-computed tomographyMicro-finite element analysisTrabecular bone remodelingTRAP deficiency

Identifiers

PMID39021958
PMCPMC11252717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.