Evidence map›Paper›PMID 39021833›Full record

ArticleFrontiers in pharmacology2024

Falls in hospitalized older adults and the use of fall risk-increasing drugs and anticholinergic medications in Colombia: a case‒control study.

Manuel E Machado-Duque, Lina Camacho-Arteaga, Mónica Sabaté, Xavier Vidal-Guitart, Jorge E Machado-Alba

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Manuel E Machado-DuqueDepartmento de Farmacología, Terapeutica y Toxicología, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Lina Camacho-ArteagaDepartmento de Farmacología, Terapeutica y Toxicología, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Mónica SabatéDepartmento de Farmacología, Terapeutica y Toxicología, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Xavier Vidal-GuitartDepartmento de Farmacología, Terapeutica y Toxicología, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Jorge E Machado-AlbaGrupo de Investigación en Farmacoepidemiologia y Farmacovigilancia, Universidad Tecnológica de Pereira-Audifarma SA, Risaralda, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In-hospital falls are multicausal in older hospitalized patients. Drugs with anticholinergic load and psychotropic effects can increase the risk of falling. Objective: This study aimed to determine the associations between fall risk-increasing drugs (FRIDs) and the anticholinergic risk score (ARS) with falls in hospitalized older hospitalized patients. Methods: This was a case‒control study of patients ≥65 years of age of either sex treated in four clinics in Colombia between 2018 and 2020. Each patient who suffered a fall during hospitalization was matched with four hospitalized patients who did not. Sociodemographic, clinical, and pharmacologic variables and the use of the ARS and FRIDs were evaluated. The risk associated with FRIDs was estimated using conditional logistic regression. Results: There were 250 patients and 1,000 controls (ratio of 1:4), with a mean age of 77.4 ± 7.4 years and a predominance of men ( Conclusion: There is an association between suffering a fall and the use of drugs with anticholinergic load or FRIDs in hospitalized adults more than 65 years of age in Colombia.

Indexed as

cholinergic antagonistselderly agedfall risk-increasing drugsfallshospital inpatients

Identifiers

PMID39021833
PMCPMC11251958

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.