Evidence map›Paper›PMID 39021495›Full record

ArticleAnimal reproduction2024

Is FSH combined with equine chorionic gonadotropin able to modify lipid metabolism in bovine superstimulated antral follicles?

Priscila Helena Santos, Fernanda Fagali Franchi, Sarah Gomes Nunes, Patricia Kubo Fontes, Alan Brunholi Giroto, Fernanda Mani, Anthony César de Souza Castilho

Abstract read
In one paragraph

Article in Animal reproduction, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Priscila Helena SantosDepartamento de Biofísica e Farmacologia, Instituto de Biociências, Universidade Estadual Paulista "Júlio de Mesquita Filho", Botucatu, SP, Brasil.ORCID 0000-0001-9858-1306
Fernanda Fagali FranchiDepartamento de Biofísica e Farmacologia, Instituto de Biociências, Universidade Estadual Paulista "Júlio de Mesquita Filho", Botucatu, SP, Brasil.ORCID 0000-0002-9859-0576
Sarah Gomes NunesDepartamento de Biofísica e Farmacologia, Instituto de Biociências, Universidade Estadual Paulista "Júlio de Mesquita Filho", Botucatu, SP, Brasil.ORCID 0000-0002-7957-1660
Patricia Kubo FontesDepartamento de Biofísica e Farmacologia, Instituto de Biociências, Universidade Estadual Paulista "Júlio de Mesquita Filho", Botucatu, SP, Brasil.ORCID 0000-0002-4280-9575
Alan Brunholi GirotoDepartamento de Ciência Animal, Universidade do Oeste Paulista, Presidente Prudente, SP, Brasil.ORCID 0000-0001-5963-5930
Fernanda ManiDepartamento de Química e Bioquímica, Instituto de Biociências, Universidade Estadual Paulista "Júlio de Mesquita Filho", Botucatu, SP, Brasil.ORCID 0000-0001-9137-7783
Anthony César de Souza CastilhoDepartamento de Ciência Animal, Universidade do Oeste Paulista, Presidente Prudente, SP, Brasil.ORCID 0000-0003-1666-7021

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid metabolism is essential for ensuring oocyte maturation and embryo development. β-Oxidized fatty acids (FA) are a potent source of energy for cells, particularly for bovine somatic follicular cells. Superstimulatory protocols using follicle stimulating hormone (FSH) or FSH combined with equine chorionic gonadotropin (eCG) are capable of stimulating the follicular microenvironment and drive the expression of biomarker genes associated with lipid metabolism in the cumulus-oocyte complex (COC) for better embryo development. In this study, we assesed the effects of FSH and FSH/eCG protocols on the expression of genes related to lipid metabolism in bovine granulosa cells (GCs). Further, we measured triglyceride levels in follicular fluid (FF) obtained from both superstimulatd and non-superstimulated cows (synchronized cows). In summary, superstimulation with gonadotropins maintained the TG levels in bovine FF and ensured GCs mRNA abundance of

Indexed as

bovinefollicle microenvironmentgene expressionsuperovulationtriglycerides

Identifiers

PMID39021495
PMCPMC11253788

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.