Evidence map›Paper›PMID 39021389›Full record

ArticleFrontiers in chemistry2024

Discovery and prospects of new heterocyclic Isatin-hydrazide derivative with a novel role as estrogen receptor α degrader in breast cancer cells.

Muhammad Nouman Arif, Sadia Sarwar, Farhat Firdous, Rahman Shah Zaib Saleem, Humaira Nadeem, Abir Abdullah Alamro, Amani Ahmad Alghamdi, Atekah Hazza Alshammari, Omer Farooq, Rashid Ali Khan and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Muhammad Nouman ArifPharmaceutical Chemistry Research Lab, Department of Pharmaceutical Chemistry, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Sadia SarwarCell Culture Laboratory, Department of Pharmacognosy, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Farhat FirdousDepartment of Chemistry and Chemical Engineering, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences (LUMS), Defence Housing Authority, Lahore, Pakistan.
Rahman Shah Zaib SaleemDepartment of Chemistry and Chemical Engineering, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences (LUMS), Defence Housing Authority, Lahore, Pakistan.
Humaira NadeemPharmaceutical Chemistry Research Lab, Department of Pharmaceutical Chemistry, Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan.
Abir Abdullah AlamroDepartment of Biochemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Amani Ahmad AlghamdiDepartment of Biochemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Atekah Hazza AlshammariDepartment of Biochemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Omer FarooqShifa College of Pharmaceutical Sciences, Shifa Tameer-e-Millat University, Islamabad, Pakistan.
Rashid Ali KhanShifa College of Pharmaceutical Sciences, Shifa Tameer-e-Millat University, Islamabad, Pakistan.
Amir FaisalDepartment of Life Sciences, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences (LUMS), Lahore, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antiproliferative activitybreast cancerestrogen receptorisatin–hydrazide derivativesmolecular dockingmolecular dynamics simulations

Identifiers

PMID39021389
PMCPMC11252035

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.