Evidence map›Paper›PMID 39021244›Full record

ArticleInternational journal of dermatology2025

Experience of living with psoriasis in Brazil: a Global Psoriasis Atlas online survey.

Jaquelini Barboza da Silva, Alison K Wright, André V E Carvalho, Christopher E M Griffiths, Darren M Ashcroft

Abstract read
In one paragraph

Article in International journal of dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jaquelini Barboza da SilvaDepartment of Life Sciences, University of Santa Cruz do Sul, Santa Cruz do Sul, Brazil.
Alison K WrightCentre for Pharmacoepidemiology and Drug Safety, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, NIHR Manchester Biomedical Research Centre, University of Manchester, Manchester, UK.ORCID https://orcid.org/0000-0002-8418-8332
André V E CarvalhoPsoriasis Outpatient Clinic, Hospital Moinhos de Vento, Porto Alegre, Brazil.
Christopher E M GriffithsCentre for Dermatology Research, NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
Darren M AshcroftCentre for Pharmacoepidemiology and Drug Safety, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, NIHR Manchester Biomedical Research Centre, University of Manchester, Manchester, UK.

Funding

Boehringer IngelheimBristol Myers SquibbGlobal Psoriasis Atlas (GPA)JanssenLEO Foundation
6 · The paper itself

Abstract

backgroundPsoriasis significantly burdens patients' lives, but there is limited data on this in Brazil.

methodsBetween May 2022 and January 2023, we conducted a cross-sectional online survey of 563 Brazilian residents aged ≥18 years who had been diagnosed with psoriasis. Spearman's correlation (r) was used to test the correlation between self-assessed disease severity (Simplified Psoriasis Index [saSPI] extent score; range 0 [clear/minor] to 40 [widespread/severe]) and health-related quality of life (QoL, score of 1 means perfect health) and capability (ICECAP-A: score of 1 means full capability) measures. Multivariable linear regression was used to identify predictors of QoL and capability. A thematic analysis examined the free-text responses and identified common themes.

resultsThe mean age of participants was 42.1 ± 12.4 years, and over half had at least one other long-term condition. The mean QoL score was 0.59 ± 0.25, and the mean capability score was 0.71 ± 0.21. At the time of survey completion, over 80% of respondents reported some level of pain and/or discomfort, and 86% reported feeling anxious and/or depressed. The mean self-assessed saSPI was 7.8 ± 8.6, which negatively correlated with health-related QoL (r = -0.49, P < 0.05) and capability (r = -0.44, P < 0.05). Significant predictors of poorer QoL and reduced capability included high saSPI, number of psoriasis flares and comorbidities, female gender, Black ethnicity, and employment status (unemployed, long-term sick). Frequently reported areas that impacted patients were social stigma/prejudice, powerlessness, lack of education and public awareness, and difficulty obtaining appropriate care/treatment.

conclusionsWe found that the clinical manifestations, severity, and associated comorbidities of psoriasis negatively impacted health-related QoL and capability, along with feelings of stigmatization and barriers to specialist treatment. This highlights the need for better access to care and awareness of the disease to improve the lives of people living with psoriasis in Brazil.

Indexed as

PsoriasisQuality of LifeAdolescentAdultAgedBrazilCross-Sectional StudiesFemaleHumansMaleMiddle AgedSeverity of Illness IndexSocial StigmaSurveys and QuestionnairesYoung Adultaccess to careinflammatory diseasespsoriasisquality of lifesocial stigma

Identifiers

PMID39021244
PMCPMC11771568

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.