Evidence map›Paper›PMID 39021170›Full record

ReviewCardiovascular & hematological disorders drug targets2024

Kounis Syndrome: Review of Clinical Cases.

Sergey Yakushin, Arzu Gurbanova, Kristina Pereverzeva

Abstract readReview
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Review in Cardiovascular & hematological disorders drug targets, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sergey YakushinDepartment of Hospital Therapy with a Course of Medical and Social Expertise, Federal State Budgetary Educational Institution of Higher Education, "Ryazan State Medical University Named after Academician I.P. Pavlov" of the Ministry of Health of the Russian Federation, Ryazan, 390026, Russia.ORCID 0000-0002-1394-3791
Arzu GurbanovaDepartment of Hospital Therapy with a Course of Medical and Social Expertise, Federal State Budgetary Educational Institution of Higher Education, "Ryazan State Medical University Named after Academician I.P. Pavlov" of the Ministry of Health of the Russian Federation, Ryazan, 390026, Russia.ORCID 0000-0001-9767-1027
Kristina PereverzevaDepartment of Hospital Therapy with a Course of Medical and Social Expertise, Federal State Budgetary Educational Institution of Higher Education, "Ryazan State Medical University Named after Academician I.P. Pavlov" of the Ministry of Health of the Russian Federation, Ryazan, 390026, Russia.ORCID 0000-0001-6141-8994

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKounis syndrome is defined as a combination of acute coronary syndrome and allergic reactions.

objectiveIn this review, we aim to describe the etiological, clinical, and diagnostic characteristics of Kounis syndrome.

methodsA literature search using PubMed was conducted for the past 32 years using keywords, resulting in the selection of 761 scientific papers. From these, 217 articles describing 235 clinical cases were selected. Patients under 18 years of age or without a confirmed diagnosis were excluded.

resultsAmong the 235 patients, type I Kounis syndrome was observed in 49.7%, type II in 27.2%, type III in 5.9%, and a combination of types I and II in 1.0%; in 16.2%, it was not possible to classify the type of Kounis syndrome. The median age was 57 years, and 68.5% of the patients were male. The most common causes were antibiotics (32.3%) and non-steroidal anti-inflammatory drugs (24.3%). The clinical features included chest pain (59.1%), hypotension (74.2%), itching (30.6%), and dyspnea (30.6%). Electrocardiographic monitoring revealed ST-segment elevation in 42.9% and was normal in only 5.5% of patients. Coronary angiography was performed in 80.4% of the patients, revealing unchanged coronary arteries in 50.3% of cases. Сonclusion: Allergic myocardial infarction is a serious complication of drug therapy.

Indexed as

Kounis SyndromeElectrocardiographyFemaleHumansMaleMiddle Agedacute coronary syndromeallergic myocardial infarctionclinical case.drug allergyKounis syndromestent

Identifiers

PMID39021170

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