Evidence map›Paper›PMID 39020529›Full record

ReviewRomanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie

Metallic nanomaterials - targeted drug delivery approaches for improved bioavailability, reduced side toxicity, and enhanced patient outcomes.

George Alexandru Croitoru, Diana Cristina Pîrvulescu, Adelina Gabriela Niculescu, Alexandru Mihai Grumezescu, Alexandru Mihai Antohi, Carmen Larisa Nicolae

Abstract readReview
In one paragraph

Review in Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Toxicity of nanostructures in drug delivery applications.Pharmaceutical science advances · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

George Alexandru CroitoruFaculty of Chemical Engineering and Biotechnology, National University of Science and Technology Politehnica, Bucharest, Romania; adelina.niculescu@upb.ro.
Diana Cristina Pîrvulescu
Adelina Gabriela Niculescu
Alexandru Mihai Grumezescu
Alexandru Mihai Antohi
Carmen Larisa Nicolae

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper explores the integral role of metallic nanomaterials in drug delivery, specifically focusing on their unique characteristics and applications. Exhibiting unique size, shape, and surface features, metallic nanoparticles (MNPs) (e.g., gold, iron oxide, and silver NPs) present possibilities for improving medication efficacy while minimizing side effects. Their demonstrated success in improving drug solubility, bioavailability, and targeted release makes them promising carriers for treating a variety of diseases, including inflammation and cancer, which has one of the highest rates of mortality in the world. Furthermore, it is crucial to acknowledge some limitations of MNPs in drug delivery before successfully incorporating them into standard medical procedures. Thus, challenges such as potential toxicity, issues related to long-term safety, and the need for standardized production methods will also be addressed.

Indexed as

Biological AvailabilityDrug Delivery SystemsMetal NanoparticlesHumansNanostructures

Identifiers

PMID39020529
PMCPMC11384046

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.