Evidence map›Paper›PMID 39020418›Full record

ArticleHarm reduction journal2024

Use and perceptions of Cannabidiol among individuals in treatment for opioid use disorder.

Christopher Kudrich, Rebecca Chen, Yuan Meng, Keren Bachi, Yasmin L Hurd

Abstract read
In one paragraph

Article in Harm reduction journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christopher KudrichDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Addiction Institute of Mount Sinai, 1399 Park Ave, Room 3-330, New York, NY, 10029, USA. ckudrich@mssm.edu.
Rebecca ChenIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Yuan MengDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Addiction Institute of Mount Sinai, 1399 Park Ave, Room 3-330, New York, NY, 10029, USA.
Keren BachiDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Addiction Institute of Mount Sinai, 1399 Park Ave, Room 3-330, New York, NY, 10029, USA.
Yasmin L HurdDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Addiction Institute of Mount Sinai, 1399 Park Ave, Room 3-330, New York, NY, 10029, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCannabidiol (CBD) is a widely available cannabis product with many claims as to potential health benefits including alleviating symptoms related to opioid use disorder (OUD). However, little is known as to how individuals with OUD perceive CBD, to what extent they may already be using CBD, and for what purposes.

methodsA survey was conducted among individuals receiving treatment for OUD at the Addiction Institute of Mount Sinai in New York City from July 2021 to August 2023. The survey consisted of demographic questions, questions about opioid use, CBD use, and perceptions regarding CBD. Statistical analysis using ordinal logistic regression was employed to compare perceptions between CBD users and non-users while adjusting for age and race.

resultsAmong 587 respondents, 550 completed the survey. Among all survey completers, 129 (23%) reported a history of using CBD for a variety of reasons including: anxiety (81, 62.8%), pain (65, 50.4%), sleep (63, 48.8%), depression (62, 48.1%), recreational purposes (32, 24.8%), or for other reasons (8, 6.2%). Of note, 22 (17.1%) respondents reported using CBD to control their addiction and 54 (41.9%) reported using CBD to ease opioid withdrawal symptoms. CBD users demonstrated more positive perceptions regarding its legality (β = 0.673, OR = 1.960, 95% CI [1.211, 3.176], p = .006), social acceptance (β = 0.718, OR = 2.051, 95% CI [1.257, 3.341], p = .004), and therapeutic potential compared to non-users. CBD users also had a more positive view of its potential future role in managing addiction (β = 0.613, OR = 1.846, 95% CI [1.181, 2.887], p = .007).

conclusionsThis study highlights a significant association between CBD usage and progressive views regarding CBD among individuals with OUD, suggesting a growing interest in CBD as a potential adjunctive therapy for individuals in substance use treatment. Some patients are already using CBD for anxiety, pain, sleep, depression, or as a harm reduction intervention to control their addiction or for opioid withdrawal symptoms. These findings underscore the importance of integrating patient perspectives into future research and treatment strategies involving CBD in the context of OUD.

Indexed as

CannabidiolOpioid-Related DisordersAdultFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedNew York CitySurveys and QuestionnairesYoung AdultCannabidiolBuprenorphineCannabidiolCannabisCBDMethadoneOpioid use disorder

Identifiers

PMID39020418
PMCPMC11253449

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.