Evidence map›Paper›PMID 39020359›Full record

ArticleJournal of neuroinflammation2024

Morphotype-specific calcium signaling in human microglia.

Sofia Nevelchuk, Bianca Brawek, Niklas Schwarz, Ariel Valiente-Gabioud, Thomas V Wuttke, Yury Kovalchuk, Henner Koch, Anke Höllig, Frederik Steiner, Katherine Figarella and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroinflammation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sofia NevelchukDepartment of Neurophysiology, Institute of Physiology, Eberhard Karls University of Tübingen, Keplerstr. 15, 72074, Tübingen, Germany.
Bianca BrawekDepartment of Neurophysiology, Institute of Physiology, Eberhard Karls University of Tübingen, Keplerstr. 15, 72074, Tübingen, Germany.
Niklas SchwarzDepartment of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
Ariel Valiente-GabioudTools for Bio-Imaging, Max-Planck-Institute for Biological Intelligence, Martinsried, Germany.
Thomas V WuttkeDepartment of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
Yury KovalchukDepartment of Neurophysiology, Institute of Physiology, Eberhard Karls University of Tübingen, Keplerstr. 15, 72074, Tübingen, Germany.
Henner KochDepartment of Epileptology, Neurology, RWTH Aachen University Hospital, Aachen, Germany.
Anke HölligDepartment of Neurosurgery, RWTH Aachen University, Aachen, Germany.
Frederik SteinerDepartment of Neurophysiology, Institute of Physiology, Eberhard Karls University of Tübingen, Keplerstr. 15, 72074, Tübingen, Germany.
Katherine FigarellaDepartment of Neurophysiology, Institute of Physiology, Eberhard Karls University of Tübingen, Keplerstr. 15, 72074, Tübingen, Germany.
Oliver GriesbeckTools for Bio-Imaging, Max-Planck-Institute for Biological Intelligence, Martinsried, Germany.
Olga GaraschukDepartment of Neurophysiology, Institute of Physiology, Eberhard Karls University of Tübingen, Keplerstr. 15, 72074, Tübingen, Germany. olga.garaschuk@uni-tuebingen.de.

Funding

Deutsche Forschungsgemeinschaft GA 654/13-2
6 · The paper itself

Abstract

backgroundKey functions of Ca

methodsWe developed a novel genetically-encoded ratiometric Ca

resultsThe data revealed marked compartmentalization of Ca

Indexed as

CalciumCalcium SignalingMicrogliaCells, CulturedFemaleHumansMaleCalciumHuman microgliaIn vitro human brain tissue modelmicroRNA-9-assisted labelingMorphotypes of resident microgliaNative microglial microenvironment

Identifiers

PMID39020359
PMCPMC11256502

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.