Evidence map›Paper›PMID 39020294›Full record

ArticleBMC emergency medicine2024

Epidemiology of maxillofacial trauma in elderly patients receiving oral anticoagulant or antithrombotic medication; a Swiss retrospective study.

David Bettschen, Dimitra Tsichlaki, Eleftherios Chatzimichail, Jolanta Klukowska-Rötzler, Martin Müller, Thomas C Sauter, Aristomenis K Exadaktylos, Mairi Ziaka, Michael Doulberis, John-Patrik Burkhard

Abstract read
In one paragraph

Article in BMC emergency medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. When Pedestrian Crossings Become Danger Zones: Trauma and Mortality Risks in Elderly Pedestrians.International journal of environmental research and public health · 2025
    Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

David BettschenDepartment of Emergency Medicine, Inselspital, University Hospital Bern, University of Bern, 3010, Bern, Switzerland.ORCID http://orcid.org/0009-0009-0958-1773
Dimitra Tsichlaki *Department of Emergency Medicine, Inselspital, University Hospital Bern, University of Bern, 3010, Bern, Switzerland.ORCID http://orcid.org/0009-0001-3171-1636
Eleftherios Chatzimichail *Department of Emergency Medicine, Inselspital, University Hospital Bern, University of Bern, 3010, Bern, Switzerland.ORCID http://orcid.org/0000-0003-4283-5260
Jolanta Klukowska-RötzlerDepartment of Emergency Medicine, Inselspital, University Hospital Bern, University of Bern, 3010, Bern, Switzerland. jolanta.klukowska-roetzler@insel.ch.ORCID http://orcid.org/0000-0001-7956-2724
Martin MüllerDepartment of Emergency Medicine, Inselspital, University Hospital Bern, University of Bern, 3010, Bern, Switzerland.ORCID http://orcid.org/0000-0003-4067-7174
Thomas C SauterDepartment of Emergency Medicine, Inselspital, University Hospital Bern, University of Bern, 3010, Bern, Switzerland.ORCID http://orcid.org/0000-0002-6646-5789
Aristomenis K ExadaktylosDepartment of Emergency Medicine, Inselspital, University Hospital Bern, University of Bern, 3010, Bern, Switzerland.ORCID http://orcid.org/0000-0002-2705-5170
Mairi ZiakaDepartment of Emergency Medicine, Inselspital, University Hospital Bern, University of Bern, 3010, Bern, Switzerland.ORCID http://orcid.org/0000-0001-5298-7925
Michael Doulberis *Gastroklinik, Private Gastroenterolgy Practice, 8810, Horgen, Switzerland.ORCID http://orcid.org/0000-0002-0396-5081
John-Patrik Burkhard *Department of Emergency Medicine, Inselspital, University Hospital Bern, University of Bern, 3010, Bern, Switzerland. jp_burkhard@me.com.ORCID http://orcid.org/0000-0002-2640-2652

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe percentage of elderly trauma patients under anticoagulation and antiplatelet agents has been rising lately. As newer agents are introduced, each comes with its own advantages and precautions. Our study covered elderly patients admitted to the ED with maxillofacial trauma while on anticoagulation (AC) or antiplatelet therapy (APT). We aimed to investigate the demographic characteristics, causes, and types of maxillofacial trauma, along with concomitant injuries, duration of hospitalisation, haemorrhagic complications, and the overall costs of care in the emergency department (ED).

methodsData were gathered from the ED of Bern University Hospital. In this retrospective analysis, patients over 65 of age were included, who presented at our ED with maxillofacial trauma between 2013 and 2019 while undergoing treatment with therapeutic AC/APT.

resultsThe study involved 188 patients with a median age of 81 years (IQR: 81 [74; 87]), of whom 55.3% (n=104) were male. More than half (54.8%, n=103) were aged 80 years or older. Cardiovascular diseases were present in 69.7% (n=131) of the patients, with the most common indications for AC/APT use being previous thromboembolic events (41.5%, n=78) and atrial fibrillation (25.5%, n=48). The predominant cause of facial injury was falls, accounting for 83.5% (n=157) of cases, followed by bicycle accidents (6.9%, n=13) and road-traffic accidents (5.3%, n=10). The most common primary injuries were fractures of the orbital floor and/or medial/lateral wall (60.1%, n=113), zygomatic bone (30.3%, n=57), followed by isolated orbital floor fractures (23.4%, n=44) and nasal bone fractures (19.1%, n=36). Fractures of the mandible occurred in 14.9% (n=28). Facial hematomas occurred in 68.6% of patients (129 cases), primarily in the midface area. Relevant facial bleeding complications were intracerebral haemorrhage being the most frequent (28.2%, n=53), followed by epistaxis (12.2%, n=23) and retrobulbar/intraorbital hematoma (9%, n=17). Sixteen patients (8.5%) experienced heavy bleeding that required emergency treatment. The in-hospital mortality rate was 2.1% (4 cases).

conclusionsThis study indicates that falls are the leading cause of maxillofacial trauma in the elderly, with the most common diagnoses being orbital, zygomatic, and nasal fractures. Haemorrhagic complications primarily involve facial hematomas, especially in the middle third of the face, with intracerebral haemorrhage being the second most frequent. Surgical intervention for bleeding was required in 8.5% of cases. Given the aging population, it is essential to improve prevention strategies and update safety protocols, particularly for patients on anticoagulant/antiplatelet therapy (AC/APT). This can ensure rapid diagnostic imaging and prompt treatment in emergencies.

Indexed as

AnticoagulantsMaxillofacial InjuriesAgedAged, 80 and overEmergency Service, HospitalFemaleFibrinolytic AgentsHumansMalePlatelet Aggregation InhibitorsRetrospective StudiesSwitzerlandAnticoagulantsFibrinolytic AgentsPlatelet Aggregation InhibitorsAnticoagulationAntiplatelet therapyBleeding complicationsElderly fallsFracturesGeriatric patientsMaxillofacial injury

Identifiers

PMID39020294
PMCPMC11256473

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.