Evidence map›Paper›PMID 39020290›Full record

ArticleBMC infectious diseases2024

Circulating 25-hydroxycholecalciferol and calcium levels, and alkaline phosphatase activity among people living with and without human immunodeficiency virus and injecting drugs in kenya.

Abel O Onyango, Nathan Shaviya, Valentine Budambula, George O Orinda, Omu Anzala, Ahmed A Aabid, Tom Were

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abel O OnyangoDepartment of Biochemistry, Microbiology, and Biotechnology, Kenyatta University, P. O. Box 43844-00100, Nairobi, Kenya.
Nathan ShaviyaDepartment of Medical Laboratory Sciences, Masinde Muliro University of Science and Technology, P. O. Box 190-50100, Kakamega, Kenya.
Valentine BudambulaDepartment of Environment and Health, Technical University of Mombasa, GPO Mombasa, P. O. Box 90420-80100, Mombasa, Kenya.
George O OrindaDepartment of Biochemistry, Microbiology, and Biotechnology, Kenyatta University, P. O. Box 43844-00100, Nairobi, Kenya.
Omu AnzalaKenya AIDS Vaccine Initiative - Institute of Clinical Research, University of Nairobi, P. O. Box 30197-00100, Nairobi, Kenya.
Ahmed A AabidBomu Hospital, P.O. Box 95683-80106, Mombasa, Kenya.
Tom WereDepartment of Medical Microbiology and Parasitology, Masinde Muliro University of Science and Technology, P. O. Box 190-50100, Kakamega, Kenya. mugogwe@yahoo.com.

Funding

Programatic-Strengthening Medical Education for Improved Health Outcomes in KenyaR24TW008889 · FIC · UNIVERSITY OF NAIROBI · PI KIBWAGE, ISAAC ONGUBO · 2010 to 2014
$10.4M
FIC NIH HHS NIH 1R24TW008889FIC NIH HHS R24 TW008889National Research Fund, Kenya NCST/5/003/065
6 · The paper itself

Abstract

backgroundPeople who inject drugs (PWID) and living with the human immunodeficiency virus (PLHIV) are at higher risk of suffering marked derangements in micronutrient levels, leading to poor disease and treatment outcomes. Consequently, this can be monitored by measuring key biomarkers, such as total circulating (serum) 25-hydroxycholecalciferol (25(OH)D

methodsThis cross-sectional study compared serum concentrations of 25(OH)D

resultsCirculating 25(OH)D

conclusionThis study suggests that HIV-1 infection and HAART, including injection substance use, decrease circulating 25(OH)D

Indexed as

Alkaline PhosphataseCalcifediolCalciumHIV InfectionsAdultAntiretroviral Therapy, Highly ActiveCross-Sectional StudiesFemaleHumansKenyaMaleMiddle AgedSubstance Abuse, IntravenousYoung AdultAlkaline PhosphataseCalcifediolCalcium25-hydroxycholecalciferolAlkaline phosphataseCalciumPeople-living-with-HIVPeople-who-inject-drugs

Identifiers

PMID39020290
PMCPMC11256408

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.