Evidence map›Paper›PMID 39020245›Full record

ArticleDrug delivery and translational research2025

A magnetic-guided nano-antibacterial platform for alternating magnetic field controlled vancomycin release in staphylococcus aureus biofilm eradication.

Zhi Huang, Yuankai Li, Wang Yin, Randy Bachelard Nziengui Raby, Haifeng Liang, Bo Yu

Abstract read
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In one paragraph

Article in Drug delivery and translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Active components ofFrontiers in cellular and infection microbiology · 2026
    Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhi HuangInstitute of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha, 410083, China.
Yuankai LiInstitute of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha, 410083, China.
Wang YinInstitute of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha, 410083, China.
Randy Bachelard Nziengui RabyInstitute of Biomedical Engineering, School of Basic Medical Sciences, Central South University, Changsha, 410083, China.
Haifeng LiangOrthopedic and Traumatology Department, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China. lianghaifong@qq.com.ORCID 0000-0001-7654-4918
Bo YuOrthopedic and Traumatology Department, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China. gzyubo@163.com.

Funding

National Natural Science Foundation of China 81974323Natural Science Foundation of Guangdong Province 2020A1515010055Science and Technology Development Plan Project of Chenzhou zdyf201993
6 · The paper itself

Abstract

Bacterial resilience within biofilms, rendering them up to 1000 times more resistant to antibiotic drugs, poses a formidable challenge. This study introduces a targeted biofilm eradication strategy, termed "target-penetration-killing-eradication", implemented through magnetic micro-robotic technology. Specifically, we present the development of a magnetic-guided nano-antibacterial platform designed for alternating magnetic field (AMF) controlled vancomycin release in the eradication of Staphylococcus aureus biofilms. To address the issue of premature vancomycin release in physiological conditions, we employed a temperature-sensitive linking agent, 4,4'-azobis(4-cyano valeric acid), facilitating the conjugation of vancomycin onto Fe

Indexed as

Anti-Bacterial AgentsBiofilmsStaphylococcus aureusVancomycinDelayed-Action PreparationsDrug LiberationMagnetic FieldsMicrobial Sensitivity TestsNanocompositesAnti-Bacterial AgentsDelayed-Action PreparationsVancomycinAlternating Magnetic FieldBiofilmsControlled releaseFe3O4

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.