Evidence map›Paper›PMID 39020176›Full record

ArticleNature2024

Identification of plant transcriptional activation domains.

Nicholas Morffy, Lisa Van den Broeck, Caelan Miller, Ryan J Emenecker, John A Bryant, Tyler M Lee, Katelyn Sageman-Furnas, Edward G Wilkinson, Sunita Pathak, Sanjana R Kotha and 9 more

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. HNature · 2026
    Article
  8. Article
  9. AUXIN RESPONSE FACTOR thermostability.Nature communications · 2026
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Nicholas MorffyDepartment of Biology, Duke University, Durham, NC, USA.
Lisa Van den BroeckDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC, USA.ORCID 0000-0003-0226-0757
Caelan MillerDepartment of Biology, Duke University, Durham, NC, USA.ORCID 0009-0001-5944-2327
Ryan J EmeneckerDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-7055-2773
John A BryantBiological Systems Engineering, Virginia Tech, Blacksburg, VA, USA.
Tyler M LeeDepartment of Biology, Duke University, Durham, NC, USA.ORCID 0009-0005-5806-0385
Katelyn Sageman-FurnasDepartment of Biology, Duke University, Durham, NC, USA.ORCID 0000-0003-2878-2027
Edward G WilkinsonDepartment of Biology, Duke University, Durham, NC, USA.
Sunita PathakDepartment of Biology, Duke University, Durham, NC, USA.
Sanjana R KothaCenter for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.
Angelica LamCenter for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.
Saloni MahatmaDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC, USA.
Vikram PandeDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC, USA.ORCID 0009-0005-6657-1898
Aman WaooDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC, USA.ORCID 0009-0008-5707-3506
R Clay WrightBiological Systems Engineering, Virginia Tech, Blacksburg, VA, USA.ORCID 0000-0001-7125-3943
Alex S HolehouseDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-4155-5729
Max V StallerCenter for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.ORCID 0000-0001-9094-5697
Rosangela SozzaniDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC, USA.ORCID 0000-0003-3316-2367
Lucia C StraderDepartment of Biology, Duke University, Durham, NC, USA. lucia.strader@duke.edu.ORCID 0000-0002-7600-7204

Funding

Cell and Molecular Biology Training ProgramT32GM142605 · NIGMS · DUKE UNIVERSITY · PI MICHAEL S BOYCE, Stefano Di Talia · 2021 to 2026
$3.7M
NIGMS administrative equipment supplement for R35 GM136338-02R35GM136338 · NIGMS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Lucia Strader · 2020 to 2026
$3.2M
Understanding and Engineering Chemically Activated Ubiquitin LigasesR35GM150856 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Robert Clay Wright · 2023 to 2026
$1.5M
NIGMS NIH HHS R35 GM136338NIGMS NIH HHS R35 GM150856NIGMS NIH HHS T32 GM142605
6 · The paper itself

Abstract

Gene expression in Arabidopsis is regulated by more than 1,900 transcription factors (TFs), which have been identified genome-wide by the presence of well-conserved DNA-binding domains. Activator TFs contain activation domains (ADs) that recruit coactivator complexes; however, for nearly all Arabidopsis TFs, we lack knowledge about the presence, location and transcriptional strength of their ADs

Indexed as

ArabidopsisArabidopsis ProteinsGene Expression Regulation, PlantProtein DomainsTranscriptional ActivationTranscription FactorsConserved SequenceDatasets as TopicIndoleacetic AcidsIntrinsically Disordered ProteinsMolecular Sequence AnnotationNeural Networks, ComputerProteomeArabidopsis ProteinsIndoleacetic AcidsIntrinsically Disordered ProteinsProteomeTranscription Factors

Identifiers

PMID39020176
PMCPMC11589624

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.