Evidence map›Paper›PMID 39020161›Full record

ArticleJournal of exposure science & environmental epidemiology2025

Exploring associations between the Phthalate Environmental Reproductive Health Literacy (PERHL) scale & biomarkers of phthalate exposure: A pilot study.

Kathryn S Tomsho, Marlee R Quinn, Emma V Preston, Gary Adamkiewicz, Tamarra James-Todd

Abstract read
In one paragraph

Article in Journal of exposure science & environmental epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kathryn S TomshoDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA. ktomsho@hsph.harvard.edu.ORCID http://orcid.org/0000-0003-1898-5728
Marlee R QuinnDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Emma V PrestonDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Gary AdamkiewiczDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Tamarra James-ToddDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
The HSPH Education and Research Center of Occupational Safety and HealthT42OH008416 · OH · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI CHRISTIANI, DAVID C · 2005 to 2025
$30.5M
Phthalates, Gestational Diabetes, and Markers of Type 2 Diabetes Risk in WomenR01ES026166 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI JAMES-TODD, TAMARRA M · 2016 to 2021
$2.9M
Pregnancy and postpartum as vulnerable exposure windows: phthalates and maternal cardiometabolic healthR01ES033185 · NIEHS · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Emily S Barrett, SUSAN W GROTH · 2022 to 2026
$2.8M
Pregnancy and postpartum as vulnerable exposure windows: phthalates and maternal cardiometabolic healthR56ES033185 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI JAMES-TODD, TAMARRA M · 2021 to 2021
$173k
NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES026166NIEHS NIH HHS R01 ES033185NIEHS NIH HHS R56 ES033185NIOSH CDC HHS T42 OH008416
6 · The paper itself

Abstract

backgroundPerinatal exposure to phthalates is associated with adverse health impacts for parents and children. The field of environmental health literacy seeks to measure how environmental health information is conceptualized and used to inform behaviors. We assessed whether scores on the validated Phthalate Environmental Reproductive Health Literacy (PERHL) scale were associated with biomarkers of phthalate exposure.

methods42 members of the Environmental Reproductive and Glucose Outcomes (ERGO) cohort completed the PERHL scale and provided spot urine samples. Phthalate summary measures for model outcomes were created by calculating molar sums of specific gravity-corrected metabolite concentrations representing exposure to parent phthalate, Di(2-ethylhexyl)phthalate (DEHP), personal care product (PCP)-associated phthalates, and parent butyl-phthalates. Linear regression models were used to estimate the associations of the PERHL scale scores with phthalate summary measures, controlling for educational attainment (college degree or higher vs. no college degree), age (years), and race and ethnicity (non-Hispanic White vs. non-White).

resultsHigher scores on the PERHL Scale and subscales were generally associated with lower ΣDEHP, Σbutyl, and ΣPCP metabolite concentrations. A one-point increase in the 'Protective Behavior/Risk Control' subscale score was significantly associated with a -30.3% (95% CI: -50.1, -2.6) decrease in ΣDEHP, and a -30.6% (95% CI: -51.5, -0.63) decrease in Σbutyl metabolite concentrations.

Indexed as

Environmental ExposureEnvironmental HealthEnvironmental PollutantsHealth LiteracyPhthalic AcidsReproductive HealthAdultBiomarkersFemaleHumansMalePilot ProjectsBiomarkersEnvironmental Pollutantsphthalic acidPhthalic Acidsbiomarkers of exposureenvironmental health literacyphthalatespsychometric scale

Identifiers

PMID39020161
PMCPMC12199996

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.