Evidence map›Paper›PMID 39020096›Full record

ReviewMedizinische Klinik, Intensivmedizin und Notfallmedizin2025

[Abnormal thyroid markers in critically ill patients-harmless irritation or a real problem?]

Lina Jegodzinski, Georg Serfling, Friedhelm Sayk

Abstract readEnglish AbstractReview
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In one paragraph

Review in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lina JegodzinskiMedizinische Klinik I, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23560, Lübeck, Deutschland.
Georg SerflingMedizinische Klinik I, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23560, Lübeck, Deutschland.
Friedhelm SaykMedizinische Klinik I, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23560, Lübeck, Deutschland. friedhelm.sayk@uksh.de.ORCID http://orcid.org/0000-0002-3437-3265

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAbnormal thyroid markers are a frequent occurrence in emergency and intensive care medicine. Correct interpretation of their clinical relevance and distinction from a primary thyroid disease, particularly prior to potential administration of iodine-containing antiarrhythmic drugs such as amiodaron or radiocontrast agents, are both essential and challenging.

objectiveThis article aims to present the pathophysiology of abnormal thyroid markers in acute or protracted critical disease. Their relevance for administration of amiodaron or iodine-containing radiocontrast agents is discussed, and concrete practical recommendations are presented. MATERIALS AND

methodsThe current work comprises a discussion of expert recommendations, guidelines, and basic research. RESULTS AND

conclusionApproximately one third of intensive care patients develop non-thyroidal illness syndrome (NTIS) during the course of their critical disease. NTIS is characterized by a reduction in the serum concentration of fT3 and, during the course, also in those of thyroid-stimulating hormone (TSH) and fT

Indexed as

Critical CareCritical IllnessEuthyroid Sick SyndromesThyroid HormonesAmiodaroneAnti-Arrhythmia AgentsBiomarkersContrast MediaDiagnosis, DifferentialHumansIntensive Care UnitsPrognosisThyroid Function TestsThyroid GlandThyrotropinThyroxineAmiodaroneAnti-Arrhythmia AgentsBiomarkersContrast MediaThyroid HormonesThyrotropinThyroxineTriiodothyronineAmiodaroneIodinated contrast agentsLow-T3 syndromeNon-thyroidal illness syndrome (NTIS)Thyroid diseases

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.