ArticleNature2024
Mechanical release of homogenous proteins from supramolecular gels.
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Locking in stability: a biocompatible calcium-squarate framework for protein preservation under extreme stress.Chemical science · 2026Article
- In Silicon Deciphering Atomic-Scale Structural Units in Peptide Glass.Angewandte Chemie (International ed. in English) · 2026Article
- Spatially Resolved Diffusion NMR for Structurally Heterogeneous Materials.Analytical chemistry · 2026Article
- G-quartet driven adaptive hydrogels that integrate constitutional dynamics for antibacterial action and tissue repair.iScience · 2026Article
- Tailored Organogel Systems for Optimized Pesticide Delivery: Mechanistic Insights and Agricultural Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Cleavage region organizes the structural architecture of the SINE-derived B2 repressive ribozyme.Communications biology · 2026Article
- High drug-loaded supramolecular microgels enabled by controlled in-droplet self-assembly for adaptive treatment of inflammatory arthritis.Bioactive materials · 2026Article
- Multi-Stimulus Triggered Programmable Transformation of Molecular Motor Based Chiral Supramolecular Polymers in Water.Angewandte Chemie (International ed. in English) · 2026Article
- Boron Nitride Reinforced Supramolecular Gels Nano-Assembled with Fungicides toward Soil-Borne Fungal Disease Management.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Localized and sustained release of Botulinum Toxin A from supramolecular peptide hydrogel for strabismus treatment.Theranostics · 2026Article
- Strategies for Regulating the Release Kinetics of Bioactive Compounds from Biopolymeric Hydrogels.Gels (Basel, Switzerland) · 2025Review
- Polymeric particle-based antigen delivery system: From immunological engineering to clinical translation.International journal of pharmaceutics: X · 2025Review
- Advances in β-Galactosidase Research: A Systematic Review from Molecular Mechanisms to Enzyme Delivery Systems.Pharmaceutics · 2025Review
- Molecular Motif Learning as a pretraining objective for molecular property prediction.Nature communications · 2025Article
- Effect of pH on the Emergent Viscoelastic Properties of Cationic Phenylalanine-Derived Supramolecular Hydrogels.Gels (Basel, Switzerland) · 2025Article
- Self-Assembly Properties of Xylene-Derived Constitutional Isomers of Fmoc-Phenylalanine.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Adaptive peptide dispersions enable drying-induced biomolecule encapsulation.Nature materials · 2025Article
- Tripeptide armour shields encapsulated proteins.Nature materials · 2025Article
- Designing supramolecular pastes by controlling host-guest dynamics in reconfigurable networks.Nature communications · 2025Article
- Innovative Formulation Strategies for Biosimilars: Trends Focused on Buffer-Free Systems, Safety, Regulatory Alignment, and Intellectual Property Challenges.Pharmaceuticals (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A long-standing challenge is how to formulate proteins and vaccines to retain function during storage and transport and to remove the burdens of cold-chain management. Any solution must be practical to use, with the protein being released or applied using clinically relevant triggers. Advanced biologic therapies are distributed cold, using substantial energy, limiting equitable distribution in low-resource countries and placing responsibility on the user for correct storage and handling. Cold-chain management is the best solution at present for protein transport but requires substantial infrastructure and energy. For example, in research laboratories, a single freezer at -80 °C consumes as much energy per day as a small household
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.