Evidence map›Paper›PMID 39020028›Full record

Observational studyJournal of perinatology : official journal of the California Perinatal Association2024

Surfactant treatment at birth in a contemporary cohort of preterm infants with bronchopulmonary dysplasia.

Clifford Mueller, Edward G Shepherd, Matthew J Kielt, Sara Conroy, Erik A Jensen, Nicolas A Bamat, Howard Panitch, Jon Levin, Milenka Guaman Cuevas, William Truog and 3 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Clifford MuellerComprehensive Center for Bronchopulmonary Dysplasia, Nationwide Children's Hospital, Columbus, OH, USA.
Edward G ShepherdComprehensive Center for Bronchopulmonary Dysplasia, Nationwide Children's Hospital, Columbus, OH, USA.ORCID 0000-0001-6816-7059
Matthew J KieltComprehensive Center for Bronchopulmonary Dysplasia, Nationwide Children's Hospital, Columbus, OH, USA.ORCID 0000-0002-4568-9070
Sara ConroyCenter for Biostatistics, The Ohio State University, Columbus, OH, USA.ORCID 0000-0001-9155-9456
Erik A JensenDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0002-9179-8032
Nicolas A BamatDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Howard PanitchDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0001-8440-283X
Jon LevinDepartment of Pediatrics, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0002-8422-791X
Milenka Guaman CuevasDivision of Neonatology, Texas Children's Hospital, Houston, TX, USA.ORCID 0000-0002-3835-5806
William TruogCenter for Infant Pulmonary Disorders, Children's Mercy Kansas City, Kansas City, MO, USA.
Steven H AbmanDepartment of Pediatrics, University of Colorado, Denver, CO, USA.ORCID 0000-0002-7292-2085
Leif D NelinComprehensive Center for Bronchopulmonary Dysplasia, Nationwide Children's Hospital, Columbus, OH, USA. leif.nelin@nationwidechildrens.org.ORCID 0000-0002-3722-3035
BPD Collaborative

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveInitial surfactant studies demonstrated improvements in survival and need for respiratory support. However, as the use of non-invasive respiratory support has increased the use of surfactant has decreased. We examined in a contemporary cohort of BPD patients if surfactant use was associated with BPD severity. STUDY

designAn observational study using data from the BPD Collaborative Registry.

results971 infants with BPD met entry criteria, 864 (89%) had received surfactant in the first 72 h of life (SURF) and the remainder had not (no surfactant). There was an association between SURF and BPD grade, with a greater likelihood of grade 3 BPD in infants who received surfactant in the DR or who had 2 or more doses.

conclusionsWe speculate that the use of surfactant in the DR and use of multiple doses reflect the impact of perinatal factors beyond immaturity alone that increase the risk for grade 3 BPD.

Indexed as

Bronchopulmonary DysplasiaInfant, PrematurePulmonary SurfactantsRegistriesFemaleGestational AgeHumansInfant, NewbornMaleSeverity of Illness IndexPulmonary Surfactants

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.