Evidence map›Paper›PMID 39019949›Full record

Trial reportScientific reports2024

Innovative strategies for managing hallucinations by exploring effects of tDCS on source monitoring abilities.

Gaurav Sharma, Vinay Chitturi, Vivek Kumar Sharma, Rajesh Kathrotia, Pradip Barde, Naresh Parmar, Medhavi Sharma, Ragini D Singh

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gaurav SharmaDepartment of Physiology, All India Institute of Medical Sciences, Rajkot, Gujarat, India.
Vinay ChitturiDepartment of Physiology, All India Institute of Medical Sciences, Rajkot, Gujarat, India.
Vivek Kumar SharmaDepartment of Physiology, All India Institute of Medical Sciences, Rajkot, Gujarat, India.
Rajesh KathrotiaDepartment of Physiology, All India Institute of Medical Sciences, Rajkot, Gujarat, India.
Pradip BardeDepartment of Physiology, All India Institute of Medical Sciences, Rajkot, Gujarat, India.
Naresh ParmarDepartment of Physiology, All India Institute of Medical Sciences, Rajkot, Gujarat, India.
Medhavi SharmaDepartment of Obstetrics and Gynaecology, All India Institute of Medical Sciences, Rajkot, Gujarat, India.
Ragini D SinghDepartment of Biochemistry, All India Institute of Medical Sciences, Rajkot, Gujarat, India. Singh.ragini28@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This randomised, crossover, sham-controlled study explored the neural basis of source-monitoring, a crucial cognitive process implicated in schizophrenia. Left superior temporal gyrus (STG) and dorsolateral prefrontal cortex (DLPFC) were the key focus areas. Thirty participants without neurological or psychological disorders underwent offline sham and active tDCS sessions with specific electrode montage targeting the left STG and DLPFC. Source-monitoring tasks, reality monitoring (Hear-Imagine), internal source-monitoring (Say-Imagine), and external source monitoring (Virtual-Real) were administered. Paired t-test and estimation statistics was performed with Graphpad version 10.1.0. The Benjamini-Hochberg procedure was employed to control the false discovery rate in multiple hypothesis testing. A significant improvement in internal source monitoring tasks (p = 0.001, Cohen's d = 0.97) was observed, but reality monitoring tasks demonstrated moderate improvement (p = 0.02, Cohen's d = 0.44). The study provides insights into the neural mechanisms of source monitoring in healthy individuals and proposes tDCS as a therapeutic intervention, laying the foundation for future studies to refine tDCS protocols and develop individualized approaches to address source monitoring deficits in schizophrenia.

Indexed as

Cross-Over StudiesHallucinationsSchizophreniaTranscranial Direct Current StimulationAdultDorsolateral Prefrontal CortexFemaleHumansMaleTemporal LobeYoung AdultAuditory hallucinationsNeuromodulationSource monitoringTranscranial direct current stimulation

Identifiers

PMID39019949
PMCPMC11254933

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.