Evidence map›Paper›PMID 39019922›Full record

ArticleScientific reports2024

Longitudinal experiences of Canadians receiving compassionate access to psilocybin-assisted psychotherapy.

Sara de la Salle, Hannes Kettner, Julien Thibault Lévesque, Nicolas Garel, Shannon Dames, Ryan Patchett-Marble, Soham Rej, Sara Gloeckler, David Erritzoe, Robin Carhart-Harris and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. The Emergence of Psilocybin in Psychiatry and Neuroscience.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  8. A Rapid Review of Psychedelic-Assisted Therapy in the Context of Palliative Care.Journal of hospice and palliative nursing : JHPN : the official journal of the Hospice and Palliative Nurses Association · 2025
    Article
  9. ExploringJournal of fungi (Basel, Switzerland) · 2025
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sara de la Salle *Department of Psychiatry, McGill University, Montréal, Canada.
Hannes Kettner *Centre for Psychedelic Research, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK.
Julien Thibault LévesqueLady Davis Institute at the Jewish General Hospital, Montréal, Canada.
Nicolas GarelDepartment of Psychiatry and Addictology, Faculty of Medicine, Université de Montréal, 2900 Boul. Edouard-Montpetit, Montréal, Canada.
Shannon DamesHealth and Human Services, Vancouver Island University, Nanaimo, Canada.
Ryan Patchett-MarbleNorthern Ontario School of Medicine University, Thunder Bay, Canada.
Soham RejDepartment of Psychiatry, McGill University, Montréal, Canada.
Sara GloecklerDepartment of Psychiatry, McGill University, Montréal, Canada.
David ErritzoeCentre for Psychedelic Research, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK.
Robin Carhart-HarrisCentre for Psychedelic Research, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK.
Kyle T GreenwayDepartment of Psychiatry, McGill University, Montréal, Canada. Kyle.greenway@mcgill.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent clinical trials have found that the serotonergic psychedelic psilocybin effectively alleviates anxiodepressive symptoms in patients with life-threatening illnesses when given in a supportive environment. These outcomes prompted Canada to establish legal pathways for therapeutic access to psilocybin, coupled with psychological support. Despite over one-hundred Canadians receiving compassionate access since 2020, there has been little examination of these 'real-world' patients. We conducted a prospective longitudinal survey which focused on Canadians who were granted Section 56 exemptions for legal psilocybin-assisted psychotherapy. Surveys assessing various symptom dimensions were conducted at baseline, two weeks following the session (endpoint), and optionally one day post-session. Participant characteristics were examined using descriptive statistics, and paired sample t-tests were used to quantify changes from baseline to the two-week post-treatment endpoint. Eight participants with Section 56 exemptions (four females, M

Indexed as

HallucinogensPsilocybinPsychotherapyAdultAgedAnxietyCanadaCompassionate Use TrialsDepressionFemaleHumansLongitudinal StudiesMaleMiddle AgedNorth American PeopleProspective StudiesHallucinogensPsilocybinDistressPalliative carePsilocybin-assisted psychotherapyPsychedelics

Identifiers

PMID39019922
PMCPMC11254907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.