Evidence map›Paper›PMID 39019881›Full record

ArticleNature communications2024

Selective nitrogen insertion into aryl alkanes.

Zheng Zhang, Qi Li, Zengrui Cheng, Ning Jiao, Chun Zhang

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Single-carbon-atom transfer toChemical science · 2025
    Article
  4. Article
  5. Skeletal Editing Strategies Driven by Total Synthesis.Accounts of chemical research · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zheng ZhangDepartment of Chemistry, Institute of Molecular Plus, Tianjin Key Laboratory of Molecular Optoelectronic Science, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China.
Qi LiDepartment of Chemistry, Institute of Molecular Plus, Tianjin Key Laboratory of Molecular Optoelectronic Science, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China.
Zengrui ChengState Key Laboratory of Natural and Biomimetic Drugs, Chemical Biology Center, School of Pharmaceutical Sciences, Peking University, Beijing, China.ORCID http://orcid.org/0000-0003-1156-2933
Ning JiaoState Key Laboratory of Natural and Biomimetic Drugs, Chemical Biology Center, School of Pharmaceutical Sciences, Peking University, Beijing, China. jiaoning@pku.edu.cn.ORCID http://orcid.org/0000-0003-0290-9034
Chun ZhangDepartment of Chemistry, Institute of Molecular Plus, Tianjin Key Laboratory of Molecular Optoelectronic Science, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China. chunzhang@tju.edu.cn.ORCID http://orcid.org/0000-0001-6848-2868

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular structure-editing through nitrogen insertion offers more efficient and ingenious pathways for the synthesis of nitrogen-containing compounds, which could benefit the development of synthetic chemistry, pharmaceutical research, and materials science. Substituted amines, especially nitrogen-containing alkyl heterocyclic compounds, are widely found in nature products and drugs. Generally, accessing these compounds requires multiple steps, which could result in low efficiency. In this work, a molecular editing strategy is used to realize the synthesis of nitrogen-containing compounds using aryl alkanes as starting materials. Using derivatives of O-tosylhydroxylamine as the nitrogen source, this method enables precise nitrogen insertion into the Csp

Identifiers

PMID39019881
PMCPMC11255249

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.