Evidence map›Paper›PMID 39019866›Full record

ArticleCell discovery2024

Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide.

Wenzhuo Li, Qingtong Zhou, Zhaotong Cong, Qingning Yuan, Wenxin Li, Fenghui Zhao, H Eric Xu, Li-Hua Zhao, Dehua Yang, Ming-Wei Wang

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell discovery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wenzhuo Li *State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Qingtong Zhou *Department of Pharmacology, School of Basic Medical Sciences, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0001-8124-3079
Zhaotong Cong *Department of Pharmacology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Qingning YuanState Key Laboratory of Drug Research, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Wenxin LiDepartment of Pharmacology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Fenghui ZhaoState Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
H Eric XuUniversity of Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-6829-8144
Li-Hua ZhaoUniversity of Chinese Academy of Sciences, Beijing, China. zhaolihuawendy@simm.ac.cn.ORCID http://orcid.org/0000-0002-7175-5174
Dehua YangState Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. dhyang@simm.ac.cn.ORCID http://orcid.org/0000-0003-3028-3243
Ming-Wei WangDepartment of Pharmacology, School of Basic Medical Sciences, Fudan University, Shanghai, China. mwwang@simm.ac.cn.ORCID http://orcid.org/0000-0001-6550-9017

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39019866
PMCPMC11255275

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.