Evidence map›Paper›PMID 39019787›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2024

Clinicopathological characteristics of secondary trigeminal neuralgia due to cerebellopontine angle tumors.

Ying Wang, Ruijie Liu, Zhiquan Yang, Zhuanyi Yang

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Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Ying WangDepartment of Pathology, School of Basic Medical Science, Central South University, Changsha 410013. wangying79@csu.edu.cn.
Ruijie LiuDepartment of Pathology, Xiangya Hospital, Central South University, Changsha 410008.
Zhiquan YangDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008, China.
Zhuanyi YangDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008, China. neuroyzy@csu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCerebellopontine angle (CPA) tumors are a common cause of secondary trigeminal neuralgia (TN), characterized by their concealed location, slow progression, and difficulty in early detection. This study aims to explore the clinicopathological characteristics of patients with secondary TN due to CPA tumors to enhance understanding and management of secondary TN.

methodsA retrospective analysis was conducted on clinical data and pathological results of 116 patients with CPA tumor-related TN treated at Xiangya Hospital of Central South University from January 1, 2017 to December 31, 2022. The study analyzed the relationship of tumor pathological types with clinical manifestations, tumor location, surgical methods, and treatment outcomes.

resultsAmong the cases, 95.7% (111/116) were benign tumors, 3.4% (4/116) were malignant tumors, and 0.9% (1/116) were borderline tumors. Benign tumors were predominantly acoustic neuromas, meningiomas, and schwannomas. Among the patients, 46.6% (54/116) presented with isolated TN, while 53.4% (62/116) exhibited other associated symptoms depending on factors such as tumor growth location and rate. The complete resection rate in this group was over 90%, with 41.4% (48/116) of patients undergoing concurrent microvascular decompression after tumor resection, predominantly for schwannomas. The overall effective rate of surgical treatment reached 93.9%, with schwannomas showing higher efficacy rates compared with acoustic neuromas and meningiomas (

conclusionsCPA tumors are a major cause of secondary TN, predominantly benign, with occasional underdiagnosed malignant tumors. Early diagnosis and treatment significantly impact prognosis. Different tumor types vary in clinical symptoms, surgical approaches, and treatment efficacy. Surgical strategies should balance tumor resection extent and neural function preservation, with microvascular decompression as necessary.

Indexed as

Cerebellar NeoplasmsCerebellopontine AngleMeningiomaNeuroma, AcousticTrigeminal NeuralgiaDecompression, SurgicalFemaleHumansMaleMeningeal NeoplasmsMiddle AgedNeurilemmomaRetrospective Studiescerebellopontine angle tumorsclinicopathological analysissecondary trigeminal neuralgia

Identifiers

PMID39019787
PMCPMC11255189

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