ArticleRespirology (Carlton, Vic.)2024
COPD is associated with increased cardiovascular disease risk independent of phenotype.
Article in Respirology (Carlton, Vic.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Acute Physiologic and Chronic Health Evaluation II and Simplified Acute Physiology Score 3 Scores as Predictors of Mortality in Cardiac Surgery.Brazilian journal of cardiovascular surgery · 2026Observational
- Chronic obstructive pulmonary disease and risk of incident cardiovascular disease, chronic kidney disease, and death: a systematic review and meta-analysis.EClinicalMedicine · 2026Article
- Clinical and Radiological Characteristics of Symptomatic Emphysema Patients with PRISm and Pre-COPD Phenotypes: Possible Effects of Smoking Status.Biomedicines · 2026Article
- Targeted therapies for myocardial infarction based on COPD-related extracellular vesicles.Scientific reports · 2026Article
- Cardiometabolic Comorbidities in COPD: Focus on Diabetes, GLP-1 Receptor Agonists, SGLT-2 Inhibitors and Antidiabetic Drugs.Journal of clinical medicine · 2026Review
- The role of COPD and inhaled corticosteroids in major adverse cardiovascular events in cardiovascular-kidney-metabolic populations.BMC medicine · 2026Article
- Life's Essential 8 and cardiovascular health: Protective effects on chronic respiratory diseases.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Association Between Sleep Disorders and Adverse Cardiovascular Outcomes in Patients with Chronic Obstructive Pulmonary Disease: Insights from the UK Biobank.International journal of chronic obstructive pulmonary disease · 2026Article
- The Disproportionate Burden of Cardiovascular Disease in Mild-to-Moderate COPD.International journal of chronic obstructive pulmonary disease · 2026Article
- Multi‑feature Prediction Model for Coronary Heart Disease Comorbidity in Middle‑aged and Older Adults with COPD Based on Machine Learning and SHAP.International journal of chronic obstructive pulmonary disease · 2026Article
- Beyond the Lungs: A Narrative Review of Cardiopulmonary Risk Reduction and Management Perspectives in Thai COPD Patients.International journal of chronic obstructive pulmonary disease · 2026Review
- Latent profile analysis of health status and influencing factors among patients with coronary heart disease based on patient-reported outcomes.Frontiers in cardiovascular medicine · 2026Article
- NOD1 modulates chronic obstructive pulmonary disease progression via FOXA1/NLRP3-mediated regulation of pyroptosis.Frontiers in immunology · 2026Article
- Association of Cardiovascular Disease and Its Subtypes with Prognosis in Hospitalized Patients with AECOPD: A Retrospective Cohort Study.International journal of chronic obstructive pulmonary disease · 2026Article
- Development and Interpretable Machine Learning-Based Prediction of Cardiovascular Disease Risk in Chinese COPD Patients: An Analysis of the CHARLS Database.International journal of chronic obstructive pulmonary disease · 2026Article
- From clinical phenotypes to cellular mechanisms: a precision medicine framework for COPD.Frontiers in immunology · 2026Review
- Inhibition of 5-hydroxyindoleacetic acid to reduce neutrophil extracellular trap production improves lung condition in chronic obstructive pulmonary disease mice.Annals of medicine · 2025Article
- Association between multimorbidity and disability among elderly with chronic obstructive pulmonary disease in Shanghai, China: a cross-sectional study.BMC geriatrics · 2025Article
- Comprehensive Review of Comorbidities in Chronic Obstructive Pulmonary Disease and Preserved Ratio Impaired Spirometry: Insights from 2024.Tuberculosis and respiratory diseases · 2025Article
- Dietary polyunsaturated fatty acid intake and all-cause and cardiovascular mortality in patients with COPD.Nutrition & metabolism · 2025Article
Corrections and comments
- Commented on by
Authors and funding
8 authors.
Funding
Abstract
BACKGROUND AND
objectiveChronic obstructive pulmonary disease (COPD) is a leading cause of death worldwide that frequently presents with concomitant cardiovascular diseases. Despite the pathological distinction between individual COPD phenotypes such as emphysema and chronic bronchitis, there is a lack of knowledge about the impact of COPD phenotype on cardiovascular disease risk. Thus, this study aimed to utilize a nationally representative sample to investigate cardiovascular disease prevalence in patients with COPD with emphysema and chronic bronchitis phenotypes.
methodsData from 31,560 adults including 2504 individuals with COPD, collected as part of the National Health and Nutrition Examination Survey (1999-2018), were examined.
resultsA significantly increased cardiovascular disease risk, including coronary heart disease, heart failure, myocardial infarction and stroke, was identified in patients with COPD among all disease phenotypes. Particularly, compared to those without COPD, individuals with chronic bronchitis presented with 1.76 (95% CI: 1.41-2.20) times greater odds, individuals with emphysema with 2.31 (95% CI: 1.80-2.96) times greater odds, while those with a concurrent phenotype (combined chronic bronchitis and emphysema) exhibited 2.98 (95% CI: 2.11-4.21) times greater odds of reporting cardiovascular diseases.
conclusionOur data confirms that patients with COPD present an elevated risk of developing cardiovascular disease among all phenotypes, with the most marked increase being in those with concurrent chronic bronchitis and emphysema phenotypes. These findings emphasize the need for awareness and appropriate cardiovascular screening in COPD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.