Evidence map›Paper›PMID 39019209›Full record

ReviewPractical radiation oncology

Stereotactic Body Radiation Therapy for Primary Renal Cell Carcinoma: A Case-Based Radiosurgery Society Practice Guide.

Andrew B Barbour, Rituraj Upadhyay, August C Anderson, Tugce Kutuk, Ritesh Kumar, Shang-Jui Wang, Sarah P Psutka, Fatemeh Fekrmandi, Karin A Skalina, Anna M E Bruynzeel and 12 more

Abstract readCase ReportsReview
In one paragraph

Review in Practical radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Andrew B BarbourDepartment of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Seattle, Washington.
Rituraj UpadhyayDepartment of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, Ohio.
August C AndersonDepartment of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Seattle, Washington.
Tugce KutukDepartment of Radiation Oncology, Miami Cancer Institute, Baptist Health South Florida, Miami, Florida.
Ritesh KumarDepartment of Radiation Oncology, Cancer Institute of New Jersey, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, New Jersey.
Shang-Jui WangDepartment of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Sarah P PsutkaDepartment of Urology, Fred Hutchinson Cancer Center, University of Washington, Seattle, Washington.
Fatemeh FekrmandiDepartment of Radiation Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Karin A SkalinaDepartment of Radiation Oncology, Montefiore Medical Center, Bronx, New York.
Anna M E BruynzeelDepartment of Radiation Oncology, Amsterdam University Medical Center, Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Rohann J M CorreaDepartment of Radiation Oncology, London Health Sciences Centre, London, Ontario, Canada.
Alan Dal PraDepartment of Radiation Oncology, University of Miami Miller School of Medicine, Miami, Florida.
Cesar Della BianciaDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York.
Raquibul HannanDepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas.
Alexander LouieDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre and the University of Toronto, Toronto, Ontario, Canada.
Anurag K SinghDepartment of Radiation Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Anand SwaminathDivision of Radiation Oncology, Juravinski Cancer Centre, McMaster University, Hamilton, Ontario, Canada.
Chad TangDepartment of Radiation Oncology, MD Anderson Cancer Center, Houston, Texas.
Bin S TehDepartment of Radiation Oncology, Cancer Center and Research Institute, Houston Methodist Hospital, Houston, Texas.
Nicholas G ZaorskyDepartment of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve, Cleveland, Ohio.
Simon S LoDepartment of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Seattle, Washington. Electronic address: simonslo@uw.edu.
Shankar SivaDivision of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Center, University of Melbourne, Melbourne, Victoria, Australia.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Traditionally, renal cell carcinoma (RCC) was considered a radioresistant tumor, thereby limiting definitive radiation therapy management options. However, several recent studies have demonstrated that stereotactic body radiation therapy (SBRT) can achieve high rates of local control for the treatment of primary RCC. In the setting of expanding use of SBRT for primary RCC, it is crucial to provide guidance on practical considerations such as patient selection, fractionation, target delineation, and response assessment. This is particularly important in challenging scenarios where a paucity of evidence exists, such as in patients with a solitary kidney, bulky tumors, or tumor thrombus. The Radiosurgery Society endorses this case-based guide to provide a practical framework for delivering SBRT to primary RCC, exemplified by 3 cases. This article explores topics of tumor size and dose fractionation, impact on renal function and treatment in the setting of a solitary kidney, and radiation's role in the management of inferior vena cava tumor thrombus. Additionally, we review existing evidence and expert opinion on target delineation, advanced techniques such as magnetic resonance imaging guided SBRT, and SBRT response assessment.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsRadiosurgeryAgedFemaleHumansMaleMiddle AgedPractice Guidelines as Topic

Identifiers

PMID39019209
PMCPMC12278115

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.