Evidence map›Paper›PMID 39018662›Full record

ArticleThe American journal of drug and alcohol abuse2024

Disentangling the effects of racism-related stress on opioid use disorder and chronic pain outcomes.

Julio C Nunes, Oluwole O Jegede, Joao P De Aquino

Abstract read
In one paragraph

Article in The American journal of drug and alcohol abuse, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Julio C NunesDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0001-9622-3361
Oluwole O JegedeDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Joao P De AquinoDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0001-7357-8215

Funding

Schizophrenia Research FellowshipR25MH071584 · NIMH · YALE UNIVERSITY · PI Christopher John Pittenger · 2005 to 2026
$4.4M
Combination of THC and CBD as a Novel Treatment for Co-Occurring Opioid Addiction and Chronic PainR01DA060066 · NIDA · YALE UNIVERSITY · PI Joao Paulo De Aquino · 2024 to 2026
$1.3M
Cannabidiol Pharmacotherapy for Comorbid Opioid Addiction and Chronic PainK23DA052682 · NIDA · YALE UNIVERSITY · PI DE AQUINO, JOAO PAULO · 2021 to 2025
$959k
Pharmacokinetics and Pharmacodynamics of Oral and Vaporized THC in Older AdultsR21DA057240 · NIDA · YALE UNIVERSITY · PI DE AQUINO, JOAO PAULO · 2022 to 2023
$360k
NIDA NIH HHS K23 DA052682NIDA NIH HHS R01 DA060066NIDA NIH HHS R21 DA057240NIMH NIH HHS R25 MH071584
6 · The paper itself

Abstract

In recent years, Black people in the U.S. have had one of the highest increases in opioid overdose mortality rates, despite being less likely to be prescribed opioids for pain. This population is also less likely to receive medications for opioid use disorder (MOUD). Chronic pain is a central factor in understanding this crisis, as minoritized people are more likely to live with undertreated pain, a major risk factor for developing opioid use disorder (OUD). Current practices fail to effectively treat pain among persons with OUD, a missed opportunity that is worse in minoritized populations and further producing disparities. In this perspective, we discuss how racism-related stress and disparities in addiction treatments may impact the pain experience, diagnosis, treatment, contribute to developing OUD, and perpetuate stigma. This high-level perspective invites clinicians and researchers to reflect on the biopsychosocial burden imposed upon historically minoritized people with pain and OUD. To address such complex issues, multidisciplinary efforts and methodological improvements are required, imbued by antiracist values. Collaboration across disciplines is necessary toward the common goal of improving pain management and mitigating opioid mortality among minoritized populations. As antiracist perspectives inform research practices and cultural humility principles guide care, we will be better equipped to close current gaps in knowledge and address widening healthcare disparities.

Indexed as

Chronic PainOpioid-Related DisordersRacismStress, PsychologicalAnalgesics, OpioidBlack or African AmericanHealthcare DisparitiesHumansSocial StigmaUnited StatesAnalgesics, Opioidchronic paininequitiesOpioid use disorderpainracismracism-related stressstress

Identifiers

PMID39018662
PMCPMC12036823

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.