ArticleScience advances2024
In vivo mapping of cellular resolution neuropathology in brain ischemia with diffusion MRI.
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Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10citing papers in PubMed
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Who cites it
10 citing papers in PubMed.
- Steady-state water exchange in neural tissue is primarily passive and through the phospholipid bilayer.bioRxiv : the preprint server for biology · 2026Article
- Complementary Sensitivity of Fixed-Time and Fixed-Oscillation Regimes to Exchange and Structural Disorder in the Human Brain Revealed Using Oscillating-Gradient Diffusion MRI With Ultra-Strong Gradients.Magnetic resonance in medicine · 2026Article
- Brain metabolomic profiling reveals ischemia-dominant disruption of metabolic pathways and tissue homeostasis in neonatal hypoxic-ischemic brain injury.Scientific reports · 2026Article
- Monte Carlo Assessment of Accuracy for Mean Kärger Model Water Exchange Rate Estimates From Diffusional Kurtosis Time Dependence.NMR in biomedicine · 2026Article
- Quantifying Transmembrane Water Exchange by Diffusion NMR Methods: From Yeast Cells to Optic Nerve Ex Vivo.NMR in biomedicine · 2026Article
- Predicting lesion reversal in acute cerebral ischaemia via apparent diffusion coefficient threshold on diffusion-weighted MRI.European radiology · 2026Article
- Non-monotonic time- and frequency-dependent diffusion kurtosis in the human brain revealed by pulsed and oscillating gradient experiments.Magnetic resonance in medicine · 2025Article
- Significance of Subtle Diffusion Weighted Imaging Lesion Dynamics: A Comparative Analysis of Methods for Detecting Diffusion Weighted Imaging Lesion Reversal in Endovascular Stroke Treatment.Stroke (Hoboken, N.J.) · 2025Article
- Engineering clinical translation of OGSE diffusion MRI.Magnetic resonance in medicine · 2025Review
- Human gray matter microstructure mapped using neurite exchange imaging (NEXI) on a clinical scanner.Imaging neuroscience (Cambridge, Mass.) · 2025Article
Corrections and comments
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Authors and funding
12 authors.
Dan WuKey Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China.ORCID 0000-0002-9303-5821
Hong-Hsi LeeDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-3663-6559
Ruicheng BaKey Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, Zhejiang, China.ORCID 0000-0003-0475-8225
Victoria TurnbillDepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0009-0001-1710-1313
Xiaoli WangSchool of Medical Imaging, Weifang Medical School, Weifang, Shandong, China.ORCID 0000-0003-3334-6713
Yu LuoDepartment of Radiology, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, China.ORCID 0000-0003-4620-3869
Piotr WalczakDepartment of Radiology, University of Maryland, Baltimore, MD, USA.ORCID 0000-0002-3733-3322
Els FieremansCenter for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0002-1384-8591
Dmitry S NovikovCenter for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0002-4213-3050
Lee J MartinDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-8961-7020
Frances J NorthingtonDepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-4557-2646
Jiangyang ZhangCenter for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0003-0740-2662
Funding
TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Daniel K Sodickson · 2014 to 2026
$19.3MImaging Neonatal Hypoxic Ischemic InjuryR01HD074593 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FRANCES J NORTHINGTON, JIANGYANG ZHANG · 2013 to 2026
$6.8MMesoscopic Biomarkers of Neurodegeneration with Diffusion MRIR01NS088040 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FIEREMANS, ELS, NOVIKOV, DMITRY S · 2014 to 2023
$5.2MElucidating factors affecting blood levels of tau and GFAP in adults at risk for neurodegenerationU01NS114144 · NINDS · MESO SCALE DIAGNOSTICS, LLC · PI STENGELIN, MARTIN · 2020 to 2024
$3.3MQuantitative Imaging of Mouse Brain DevelopmentR01NS102904 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ZHANG, JIANGYANG · 2018 to 2022
$3.1MAdvanced therapeutic hypothermia efficacy network modeling in neonatal HIER01HD110091 · NICHD · JOHNS HOPKINS UNIVERSITY · PI EVERETT, ALLEN D, NORTHINGTON, FRANCES J · 2022 to 2025
$2.7MRevealing tissue microstructure in the brain gray matter in Alzheimer's disease using in vivo high-gradient diffusion MRIDP5OD031854 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, HONG HSI · 2021 to 2025
$2.1MPrecision Medicine for Neonatal Hypoxic-Ischemic Encephalopathy: Combined Neuroimaging Clinical Approach to Link Phenotypes to PrognosisR01NS126549 · NINDS · JOHNS HOPKINS UNIVERSITY · PI Kenichi Oishi · 2022 to 2026
$2.0MEpigenetic Regulation of Neuronal Cell DeathR01NS079348 · NINDS · JOHNS HOPKINS UNIVERSITY · PI MARTIN, LEE J · 2013 to 2014
$705kEarly Life Brain Injury and Neurodegenerative Disorders of AgingR21AG061643 · NIA · JOHNS HOPKINS UNIVERSITY · PI NORTHINGTON, FRANCES J · 2019 to 2020
$459kCholinergic neuron degeneration after HI: New target for delayed therapy of neonatal HI to improve Learning and Memory DeficitsR21NS123814 · NINDS · JOHNS HOPKINS UNIVERSITY · PI NORTHINGTON, FRANCES J · 2022 to 2023
$450kNIA NIH HHS R21 AG061643NIBIB NIH HHS P41 EB017183NICHD NIH HHS R01 HD074593NICHD NIH HHS R01 HD110091NIH HHS DP5 OD031854NINDS NIH HHS R01 NS079348NINDS NIH HHS R01 NS088040NINDS NIH HHS R01 NS102904NINDS NIH HHS R01 NS126549NINDS NIH HHS R21 NS123814NINDS NIH HHS U01 NS114144
Abstract
Noninvasive mapping of cellular pathology can provide critical diagnostic and prognostic information. Recent advances in diffusion magnetic resonance imaging enabled in vivo examination of tissue microstructures well beyond the imaging resolution. Here, we proposed to use diffusion time-dependent diffusion kurtosis imaging (
Indexed as
Brain IschemiaDiffusion Magnetic Resonance ImagingAnimalsBrainDisease Models, AnimalHumansMaleMice
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.