A Ratiometric Fast-Response Fluorescent Probe Based on Dicyanoisophorone for Monitoring HClO in Paper Test Strips and Living Mice.

Zhenzhen Wang, Ziqing Ye, Yumiao Sheng, Kedian Xu, Ruiqing Liang, Yunling Gao

Abstract read

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Article in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Zhenzhen WangState Key Laboratory Breeding Base of Green Chemistry Synthesis Technology, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 310032, China.

Ziqing YeState Key Laboratory Breeding Base of Green Chemistry Synthesis Technology, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 310032, China.

Yumiao ShengState Key Laboratory Breeding Base of Green Chemistry Synthesis Technology, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 310032, China.

Kedian XuState Key Laboratory Breeding Base of Green Chemistry Synthesis Technology, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 310032, China.

Ruiqing LiangState Key Laboratory Breeding Base of Green Chemistry Synthesis Technology, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 310032, China.

Yunling GaoState Key Laboratory Breeding Base of Green Chemistry Synthesis Technology, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 310032, China. gaoyl@zjut.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new dicyanoisophorone-based ratiometric fluorescent probe NOSA was synthesized and characterized. It showed a fast fluorescence response to HClO with the emission color change from dark green to bright red. NMR, IR, and HRMS suggested that the detection of NOSA to HClO may originate from the hydroxyl deprotection reaction by HClO on the molecule NOSA, which caused a red-shift of fluorescence. The probe NOSA displayed high selectivity and excellent anti-interference performance with a limit of detection at 3.835 × 10

Indexed as

Fluorescent DyesHypochlorous AcidPaperReagent StripsAnimalsMiceMolecular StructureOptical ImagingSpectrometry, FluorescenceFluorescent DyesHypochlorous AcidReagent StripsHypochlorous acidImaging in micePaper test stripRatiometric fluorescent probeSpiked recovery

Identifiers

PMID39018003

DOI10.1007/s10895-024-03837-z

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.