Evidence map›Paper›PMID 39017944›Full record

ArticleSkeletal radiology2025

Association of tibial slope alterations with anterior cruciate ligament (ACL) injury and mucoid degeneration.

Varun Ravi, Mahad Rehman, Shuda Xia, Avneesh Chhabra, Flavio Duarte Silva

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Article in Skeletal radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Varun RaviUT Southwestern Medical School, UT Southwestern Medical Center, Dallas, TX, USA.
Mahad RehmanUT Southwestern Medical School, UT Southwestern Medical Center, Dallas, TX, USA.
Shuda XiaUT Southwestern Medical School, UT Southwestern Medical Center, Dallas, TX, USA.
Avneesh ChhabraDepartment of Radiology, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, USA. Avneesh.chhabra@utsouthwestern.edu.
Flavio Duarte SilvaDepartment of Radiology, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare radiographic measurements of lateral tibial slope (LTS), medial TS (MTS), and coronal TS (CTS) in MRI-defined intact, injured, and mucoid-degenerated native ACL knees and determine inter-reader reliability. MATERIALS AND

methodsPatient records from 2 years at tertiary care hospitals were reviewed for individuals aged 18-100 undergoing 3-Tesla knee MRI and radiographs. Two randomly selected cohorts, control, and pathologic ACLs on MRI with 86 patients each, were age, gender, and BMI-matched. A fellowship-trained musculoskeletal radiologist reevaluated curated images, characterizing ACL status. Two trained medical students independently collected clinical data and measured slopes on blinded radiographs. ICC, Cohen's kappa, and case-control matching were performed using SPSS statistical package, with ICC and ANOVA used for comparisons.

resultsAmong 172 patients with 172 MRIs and radiographs, there were 86 controls and 86 ACL lesions. There were 108/172 (62.79%) males and 64/172 (37.21%) females. ICCs were 0.966 for MTS, 0.975 for LTS, and 0.978 for CTS. Mucoid degeneration patients had a higher BMI and were older than control (p < .05) or completely torn (p < .001) ACL patients. There was no difference in TS between normal and pathologic ACLs; however, LTS-MTS differences were larger with partial tears (2.5 ± 4.9) than normal ACLs by 4.5° (± 1.2, p < .001), complete tears by 4.5° (± 1.3, p < .001), and mucoid degeneration by 4.9° (± 1.5, p = .001).

conclusionVarious TS measurements are reliable. LTS-MTS differences are associated with different ACL lesions compared to normal ACLs.

Indexed as

Anterior Cruciate Ligament InjuriesMagnetic Resonance ImagingTibiaAdolescentAdultAgedAged, 80 and overCase-Control StudiesFemaleHumansMaleMiddle AgedReproducibility of ResultsRetrospective StudiesYoung AdultACLAnterior cruciate ligament injuryKneeMucoid degenerationTibial slope

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.